CPA6
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Official Full Name
carboxypeptidase A6 -
Overview
The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t(6;8)(q26;q13) involving this gene, have been associated with Duane retraction syndrome. -
Synonyms
CPA6;carboxypeptidase A6;Carboxypeptidase B;CBPA6_HUMAN;CPAH
Recombinant Proteins
- Chicken
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CPA6-1488C | Recombinant Chicken CPA6 | Mammalian Cell | Chicken | His |
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| CPA6-1776H | Recombinant Human CPA6 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CPA6-256H | Recombinant Human CPA6 Protein, His-tagged | E.coli | Human | His |
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| CPA6-3832M | Recombinant Mouse CPA6 Protein | Mammalian Cell | Mouse | His |
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| CPA6-7318HCL | Recombinant Human CPA6 293 Cell Lysate | HEK293 | Human | Non |
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| CPA6-1922M | Recombinant Mouse CPA6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CPA6-1922M-B | Recombinant Mouse CPA6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CPA6-2032HF | Recombinant Full Length Human CPA6 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 437 amino acids |
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| CPA6-2721H | Recombinant Human CPA6 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 130-437aa |
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Involved Pathway
CPA6 involved in several pathways and played different roles in them. We selected most pathways CPA6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CPA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CPA6 has several biochemical functions, for example, metallocarboxypeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPA6 itself. We selected most functions CPA6 had, and list some proteins which have the same functions with CPA6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ANAPC11,PRICKLE1B,ZSWIM1,LONRF3,KLF4,SUV39H2,MMP26,TET2,ADAM17A,CRIP1 |
| metallocarboxypeptidase activity | CPZ,PEPD,CPA3,AGTPBP1,CPO,FOLH1,CPB1,CPA4,CPB2,AGBL3 |
Interacting Protein
CPA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPA6.
Resources
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References
- Sapio, MR; Fricker, LD; et al. Carboxypeptidases in disease: Insights from peptidomic studies. PROTEOMICS CLINICAL APPLICATIONS 8:327-337(2014).
- Belhedi, N; Perroud, N; et al. Increased CPA6 promoter methylation in focal epilepsy and in febrile seizures. EPILEPSY RESEARCH 108:144-148(2014).
