CPA3
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Official Full Name
carboxypeptidase A3 (mast cell) -
Overview
Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a form which is obtained as a binary complex of a procarboxypeptidase A with proproteinase E and functions as a secretory granule metalloexopeptidase. -
Synonyms
CPA3;carboxypeptidase A3 (mast cell);mast cell carboxypeptidase A;carboxypeptidase A;Carboxypeptidase A3;carboxypeptidase A3 mast cell;CBPA3_HUMAN;mast cell carboxypeptidase A3;MC CPA;MC-CPA
Recombinant Proteins
- Rat
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- HEK293
- Yeast
- E.coli
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- His&GST
Involved Pathway
CPA3 involved in several pathways and played different roles in them. We selected most pathways CPA3 participated on our site, such as Metabolism of Angiotensinogen to Angiotensins,Metabolism of proteins,Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Renin-angiotensin system | CTSA,ACE,Ren1,KLK1,PRCP,ACE2,KLK1B3,KLK1B9,AGTR1B,KLK1B24 |
| Peptide hormone metabolism | GPR119,CPE,SPCS3,CDX2,ACE,EXOC8,INHA,CPN1,ATP6AP2,SLC38A8 |
| Metabolism of Angiotensinogen to Angiotensins | CPB2,CTSG,CPB1,ACE,CMA1,ATP6AP2,GZMH |
| Pancreatic secretion | PRKCB,CPB1,CELA2A,SCTR,PRSS1,CELA2B,PNLIPRP2,AMY2A4,TRPC1,AMY2A |
| Protein digestion and absorption | SLC16A10,CPA1,CELA3A,CPA2,XPNPEP2,KCNK5,ATP1B3,CPB1,COL18A1,PRCP |
| Metabolism of proteins | SUMF2,TBCB,ATPBD4,TBCA,TOMM70A,GATA6,NANP,SEC16B,TIMM9,ASNA1 |
Protein Function
CPA3 has several biochemical functions, for example, metallocarboxypeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPA3 itself. We selected most functions CPA3 had, and list some proteins which have the same functions with CPA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | EHMT1A,PPARAA,LHX2,PHC3,KLF7,DTX3,MICALL2B,NRD1B,MARCH11,CIZ1B |
| metallocarboxypeptidase activity | CPA1,CPB1,CPDB,CPD,FOLH1,AGBL5,CPA5,CPO,PEPD,AGBL3 |
Interacting Protein
CPA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPA3.
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