COL5A2
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Official Full Name
collagen, type V, alpha 2 -
Overview
Collagen alpha-2(V) chain is a protein that in humans is encoded by the COL5A2 gene. -
Synonyms
COL5A2;collagen, type V, alpha 2;collagen alpha-2(V) chain;AB collagen;type V preprocollagen alpha 2 chain;collagen, fetal membrane, A polypeptide;MGC105115
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- HEK293
- Mammalian Cell
- Human Cell
- E.coli
- GST
- mFc
- His
- Non
- His&Fc&Avi
- His&GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| COL5A2-1657H | Recombinant Human COL5A2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| COL5A2-230H | Recombinant Human COL5A2 protein, mFc-tagged | HEK293 | Human | mFc | Met1-Leu1229 |
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| COL5A2-3743M | Recombinant Mouse COL5A2 Protein | Mammalian Cell | Mouse | His |
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| COL5A2-908HCL | Recombinant Human COL5A2 cell lysate | Human Cell | Human | Non |
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| COL5A2-1867M | Recombinant Mouse COL5A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| COL5A2-1867M-B | Recombinant Mouse COL5A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| COL5A2-347H | Recombinant Human COL5A2 Protein, His/GST-tagged | E.coli | Human | His&GST | Cys82~Glu308 |
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Involved Pathway
COL5A2 involved in several pathways and played different roles in them. We selected most pathways COL5A2 participated on our site, such as Amoebiasis,Assembly of collagen fibrils and other multimeric structures,Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL5A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Collagen biosynthesis and modifying enzymes | EMID2,COL2A1,ADAMTS2,COL9A1B,TLL1,LEPREL2,COL11A1B,COL6A2,COL19A1,TLL2 |
| ECM-receptor interaction | GP1BB,ITGA8,FN1A,ITGA6,SV2A,COL4A3,GP9,VWF,LAMB3,THBS3 |
| Collagen formation | COL8A1,COL19A1,MMP13,PPIB,COL4A5,COL16A1,COL5A3B,SERPINH1A,CTSS,BMP1B |
| Focal adhesion | PIK3R2,MYL2B,PARVB,AKT2,MAPK4,PIK3R3,MAP2K1,STYK1,MYLPF,COL6A2 |
| Assembly of collagen fibrils and other multimeric structures | COL4A6,COL8A1,COL10A1A,PLEC,COL6A1,DST,COL5A3B,PCOLCE,BMP1,COL5A1 |
| Extracellular matrix organization | PCOLCEA,COL28A1,FBLN2,CEACAM1,DDR2,COL23A1,MMP13,TIMP2B,LEPRE1,SERPINH1B |
| Amoebiasis | PTK2,CD14,LAMA1,COL4A4,CD1D,LAMC3,PIK3CB,PRKACB,SERPINB1A,ACTN2 |
Protein Function
COL5A2 has several biochemical functions, for example, SMAD binding,extracellular matrix structural constituent,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL5A2 itself. We selected most functions COL5A2 had, and list some proteins which have the same functions with COL5A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SMAD binding | FOXH1,BMP2,YY1,COL3A1,BMPR1A,SKILB,USP15,ACVRL1,SKI,TOB1 |
| molecular_function | EMILIN3,GM3448,MRPL47,CRESTIN,KBTBD7,DGAT2L6,ASB1,BTN2A1,RAI2,FETUB |
| extracellular matrix structural constituent | LAMA4,COL5A1,FBLN1,COL11A1B,COL24A1,ELNA,COL27A1,COL8A2,IMPG1,FBLN2 |
| metal ion binding | ZNF560,ESYT3,PPP2CB,ZBTB8A,ANG3,ADAP1,MAT2AA,ANKFY1,GMEB1,ZFP771 |
Interacting Protein
COL5A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL5A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL5A2.
TGM2;Fbxw11
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References
- Kao, YH; Lin, YC; et al. Involvement of the nuclear high mobility group B1 peptides released from injured hepatocytes in murine hepatic fibrogenesis. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1842:1720-1732(2014).
- Banda, NK; Mehta, G; et al. Essential Role for the Lectin Pathway in Collagen Antibody-Induced Arthritis Revealed through Use of Adenovirus Programming Complement Inhibitor MAp44 Expression. JOURNAL OF IMMUNOLOGY 193:2455-2468(2014).
