CNTRL
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Official Full Name
CENPL centromere protein L [ Homo sapiens ] -
Overview
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. -
Synonyms
CENP-L;C1orf155;dJ383J4.3;RP3-383J4.1;centromere protein L;interphase centromere complex protein 33;chromosome 1 open reading frame 155;Interphase centromere complex protein 3
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Involved Pathway
CNTRL involved in several pathways and played different roles in them. We selected most pathways CNTRL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CNTRL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
CNTRL has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CNTRL itself. We selected most functions CNTRL had, and list some proteins which have the same functions with CNTRL. You can find most of the proteins on our site.
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Interacting Protein
CNTRL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNTRL here. Most of them are supplied by our site. Hope this information will be useful for your research of CNTRL.
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