CLN6
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Official Full Name
ceroid-lipofuscinosis, neuronal 6, late infantile, variant -
Overview
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. -
Synonyms
CLN6;ceroid-lipofuscinosis, neuronal 6, late infantile, variant;ceroid-lipofuscinosis neuronal protein 6;FLJ20561;HsT18960;nclf;CLN4A
Recombinant Proteins
- Human
- Chicken
- Mouse
- Dog
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- GST
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLN6-1507H | Recombinant Human CLN6 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CLN6-5007C | Recombinant Chicken CLN6 | Mammalian Cell | Chicken | His |
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| CLN6-7438HCL | Recombinant Human CLN6 293 Cell Lysate | HEK293 | Human | Non |
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| CLN6-112H | Recombinant Human CLN6 Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| CLN6-1883HF | Recombinant Full Length Human CLN6 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 311 amino acids |
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| Cln6-2194M | Recombinant Mouse Cln6 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| RFL1861CF | Recombinant Full Length Dog Ceroid-Lipofuscinosis Neuronal Protein 6 Homolog(Cln6) Protein, His-Tagged | E.coli expression system | Dog | His | Full L. Full Length (1-312) |
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| RFL29887HF | Recombinant Full Length Human Ceroid-Lipofuscinosis Neuronal Protein 6(Cln6) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-311) |
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Involved Pathway
CLN6 involved in several pathways and played different roles in them. We selected most pathways CLN6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLN6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CLN6 has several biochemical functions, for example, protein binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLN6 itself. We selected most functions CLN6 had, and list some proteins which have the same functions with CLN6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | POLDIP2,MICU1,SAP18,PNPT1,ZMYM2,BTBD1,NXF1,PHIP,MYBL2,NTS |
| protein homodimerization activity | TBX18,BAXB,BHLHB9,MYOM3,PDCD10,ACVR1,CEP57,ENO2,TIMELESS,TPD52L1 |
Interacting Protein
CLN6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLN6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLN6.
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