CLDN17

  • Official Full Name

    claudin 17
  • Overview

    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11.
  • Synonyms

    CLDN17;claudin 17;claudin-17;MGC126552;MGC126554;OTTHUMP00000101916;human CLDN17 gene for claudin-17

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Mus musculus
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • E.coli expression system
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CLDN17-1435H Recombinant Human CLDN17 Protein, GST-tagged Wheat Germ Human GST
CLDN17-3528M Recombinant Mouse CLDN17 Protein Mammalian Cell Mouse His
CLDN17-6209Z Recombinant Zebrafish CLDN17 Mammalian Cell Zebrafish His
CLDN17-7467HCL Recombinant Human CLDN17 293 Cell Lysate HEK293 Human Non
CLDN17-1729M Recombinant Mouse CLDN17 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CLDN17-1729M-B Recombinant Mouse CLDN17 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CLDN17-2046HF Recombinant Full Length Human CLDN17 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 224 amino acids
RFL189MF Recombinant Full Length Mouse Claudin-17(Cldn17) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-224)
RFL20807HF Recombinant Full Length Human Claudin-17(Cldn17) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-224)

    Involved Pathway

    CLDN17 involved in several pathways and played different roles in them. We selected most pathways CLDN17 participated on our site, such as Cell adhesion molecules (CAMs),Tight junction,Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) NLGN2B,JAM2,CLDN22,HLA-DQA2,CNTNAP1,CD226,HLA-DRB5,MAG,NFASCA,CLDNB
    Hepatitis C IRF9,CLDN8,PPP2R2D,EIF2AK4,IRF7,IFNA10,IL-8,SCARB1,MAPK8,NFKB1
    Leukocyte transendothelial migration CLDN11,ITGAM,PTK2B,MYL9,ARHGAP5,MYL12A,OCLN,RAC2,ITGB1,TXK
    Tight junction MYH3,YES1,MYH10,CLDN19,CLDN1,PARD6B,CLDN22,MYH7B,MYH1E,CDC42L2

    Protein Function

    CLDN17 has several biochemical functions, for example, identical protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN17 itself. We selected most functions CLDN17 had, and list some proteins which have the same functions with CLDN17. You can find most of the proteins on our site.

    Function Related Protein
    structural molecule activity FGB,COL15A1,KRT40,ANXA1,CLDN19,CLDN7B,CLDN7,KRT33A,SNTB2,KRT33B
    identical protein binding SHARPIN,PDGFB,TRP53,PVRL2,COMMD1,GBP5,ALDOB,CCDC155,SMURF2,PRPF19

    Interacting Protein

    CLDN17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN17 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN17.

    Resources

    References

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