CLCNKB
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Official Full Name
chloride channel Kb -
Overview
This gene is a member of the CLC family of voltage-gated chloride channels. The gene is located adjacent to a highly similar chloride channel gene on chromosome 5. This gene is syntenic with human CLCNKA (geneID:1187). -
Synonyms
CLCNKB;chloride channel Kb;chloride channel protein ClC-Kb;Bartter syndrome type 3;Chloride channel kidneyB;ClC K2;ClC-K2;ClCK2;CLCKB;CLCKB_HUMAN;hClC Kb;hClCKb;MGC24087;OTTHUMP00000011120;OTTHUMP00000011121;RP11 5P18.8;chloride channel K2;ClC-K2L;Clcnk1l
Recombinant Proteins
- Human
- Rat
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLCNKB-1423H | Recombinant Human CLCNKB Protein, GST-tagged | Wheat Germ | Human | GST |
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| CLCNKB-1430R | Recombinant Rat CLCNKB Protein | Mammalian Cell | Rat | His |
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| CLCNKB-3520M | Recombinant Mouse CLCNKB Protein | Mammalian Cell | Mouse | His |
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| CLCNKB-1088R | Recombinant Rat CLCNKB Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CLCNKB-1088R-B | Recombinant Rat CLCNKB Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| CLCNKB-1724M | Recombinant Mouse CLCNKB Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CLCNKB-1724M-B | Recombinant Mouse CLCNKB Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CLCNKB-2036HF | Recombinant Full Length Human CLCNKB Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 462 amino acids |
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Involved Pathway
CLCNKB involved in several pathways and played different roles in them. We selected most pathways CLCNKB participated on our site, such as Collecting duct acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLCNKB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Collecting duct acid secretion | ATP6V0A4,ATP4A,ATP6V0E2,CA2,ATP6V0D1,ATP6V0D2,ATP6V1G3,SLC12A7,ATP6V1G2,ATP6V1E1 |
Protein Function
CLCNKB has several biochemical functions, for example, chloride channel activity,ion channel activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLCNKB itself. We selected most functions CLCNKB had, and list some proteins which have the same functions with CLCNKB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ion channel activity | KCNS3B,CHRNA1,TRPM4C,Chrng,KCNH6A,TRPV5,GABRA6A,KCNH1B,HTR3B,TRPM1A |
| voltage-gated ion channel activity | KCNB2,NALCN,PKD2,SCN1LAB,CLIC3,CACNA1SA,CLIC1,SCN12AA,KCNJ1A.2,SCN8AA |
| voltage-gated chloride channel activity | CLCNKA,CLCN2,CLCN5,CLCN3,CLCN1A,CLCN1,CLCN4,CLCN6,CLCN4-2,CLCN7 |
| metal ion binding | ZC3H13,ENDOU2,MYLIPB,AGFG1A,NR1D4B,NEURL1AA,PPP1CC,AGFG1B,JADE3,EXTL3 |
| chloride channel activity | GRAP2,CLIC6,FXYD1,CLIC5A,GABRA4,CLIC5,CLCN7,CLCN4,CLIC4,GABRG2 |
| protein binding | FBXO34,CSNK1E,UTF1,CD163,PREP,RFESD,NAE1,ZFP488,RARB,FBXW9 |
Interacting Protein
CLCNKB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLCNKB here. Most of them are supplied by our site. Hope this information will be useful for your research of CLCNKB.
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