CLCN2
-
Official Full Name
chloride channel 2 -
Overview
This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains;chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript;variants encoding different isoforms have been found for this gene. -
Synonyms
CLCN2;chloride channel 2;chloride channel protein 2;ClC 2;CLC2;EJM6;CIC 2;CIC2;ClC-2;CLCN2_HUMAN;ECA2;ECA3;EG13;EGI11;EGMA;EJM8;OTTHUMP00000210513;OTTHUMP00000210514;OTTHUMP00000210515;OTTHUMP00000210516;EGI3;CIC-2
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CLCN2-11279H | Recombinant Human CLCN2, His-tagged | E.coli | Human | His | C-term-350a.a. | |
| CLCN2-1829H | Recombinant Human CLCN2 protein, GST-tagged | E.coli | Human | GST | 164-296 aa | |
| CLCN2-3394H | Recombinant Human CLCN2 protein, His-tagged | E.coli | Human | His | 164-296 aa | |
| CLCN2-1415H | Recombinant Human CLCN2 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| CLCN2-1425R | Recombinant Rat CLCN2 Protein | Mammalian Cell | Rat | His |
|
|
| CLCN2-3513M | Recombinant Mouse CLCN2 Protein | Mammalian Cell | Mouse | His |
|
|
| CLCN2-7475HCL | Recombinant Human CLCN2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| CLCN2-1083R | Recombinant Rat CLCN2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| CLCN2-1083R-B | Recombinant Rat CLCN2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| CLCN2-1718M | Recombinant Mouse CLCN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| CLCN2-1718M-B | Recombinant Mouse CLCN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| CLCN2-1967HF | Recombinant Full Length Human CLCN2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 38-387 amino acids |
|
Involved Pathway
CLCN2 involved in several pathways and played different roles in them. We selected most pathways CLCN2 participated on our site, such as Ion channel transport,Mineral absorption,Stimuli-sensing channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SLCO3A1,SLC9A6A,SLC39A7,SLC35A2,CLCN5,TRPM1B,ANO10A,AQP9B,CLCNK,SLC28A2 |
| Stimuli-sensing channels | CLCN7,ANO8,NHEDC1,ANO1,ANO7,TTYH2,CLIC2,TRPC4,ANO4,ANO10 |
| Mineral absorption | ATP1B4,ATOX1,SLC30A1,MT1X,SLC11A1,TF,SLC26A3,S100G,MT1H,ATP1A2 |
| Ion channel transport | CLCN5,ANO5,Ano3,TPCN1,TTYH3,ASIC1A,TRPC4APB,CLIC2,CLCNK,CLCN4 |
Protein Function
CLCN2 has several biochemical functions, for example, voltage-gated chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLCN2 itself. We selected most functions CLCN2 had, and list some proteins which have the same functions with CLCN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated chloride channel activity | CLCN1A,CLCNKB,CLCN4-2,CLCNKA,CLCN6,CLCN1,CLCN4,CLCN5,CLCN7,CLCNK |
Interacting Protein
CLCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLCN2.
b4dyc6_human;SGTA;BAG2;MLF1;PSMD2;Usp19;q53fc7_human;NUDCD3;Hacd3;q96be0_human;AARSD1;STUB1;ATXN1;PPP1CA;PEX10;NVL;SRP14;EIF4G1;RAB11FIP2
Resources
Related Services
Related Products
References
