CKLF
-
Official Full Name
chemokine-like factor -
Overview
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1). -
Synonyms
CKLF;chemokine-like factor;chemokine like factor 1 , CKLF1;C32;CKLF3;CKLF4;HSPC224;UCK 1;chemokine-like factor 1;chemokine-like factor 2;chemokine-like factor 3;chemokine-like factor 4;transmembrane proteolipid;CKLF1;CKLF2;UCK-1
Recombinant Proteins
- Human
- Rat
- Mouse
- Rhesus macaque
- Mus musculus
- Mammalian Cell
- HEK293
- Protein Conjugation
- E.coli expression system
- His
- Non
- His&Fc&Avi
Involved Pathway
CKLF involved in several pathways and played different roles in them. We selected most pathways CKLF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CKLF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CKLF has several biochemical functions, for example, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CKLF itself. We selected most functions CKLF had, and list some proteins which have the same functions with CKLF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chemokine activity | CCL11,CCL17,IL-8,CXCL32B.1,CCL28,CCL38.1,CXCL19,CCL34B.1,CCL25B,CCL4 |
Interacting Protein
CKLF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CKLF here. Most of them are supplied by our site. Hope this information will be useful for your research of CKLF.
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