CHSY3
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Official Full Name
chondroitin sulfate synthase 3 -
Synonyms
CHSY3;chondroitin sulfate synthase 3;24293;ENSG00000198108;CSS3;CHSY2;5q23.3;chondroitin sulfate synthase 3;chondroitin sulfate synthase 3;chSy-2;chondroitin synthase 2;chondroitin synthase-2;carbohydrate synthase 2;N-acetylgalactosaminyltransferase 3;chondroitin glucuronyltransferase 3;N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3;glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II;EC 2.4.1.175 EC 2.4.1.226
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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CHSY3-11236H | Recombinant Human CHSY3, His-tagged | E.coli | Human | His | 571-769a.a. | |
CHSY3-3459M | Recombinant Mouse CHSY3 Protein | Mammalian Cells | Mouse | His |
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CHSY3-5503Z | Recombinant Zebrafish CHSY3 | Mammalian Cells | Zebrafish | His |
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CHSY3-1680M | Recombinant Mouse CHSY3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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CHSY3-1680M-B | Recombinant Mouse CHSY3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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CHSY3-785H | Recombinant Human CHSY3 Protein, His-tagged | E.coli | Human | His | Glu685-Ser882 |
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Chsy3-786M | Recombinant Mouse Chsy3 Protein, His-tagged | E.coli | Mouse | His | Ala612-Ser884 |
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Involved Pathway
CHSY3 involved in several pathways and played different roles in them. We selected most pathways CHSY3 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHSY3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolic pathways | LAP3,PDXKB,ATP6V0E,B4GALT6,PPCDC,PCYT1BA,NDST3,ALDH1A2,PTGES3A,CBR3 |
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | CSGALNACT1,CHST3A,CHST15,XYLT2,XYLT1,CSGALNACT2,CHPF2,CHST7,CHST3,CHST3B |
Protein Function
CHSY3 has several biochemical functions, for example, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity,glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHSY3 itself. We selected most functions CHSY3 had, and list some proteins which have the same functions with CHSY3. You can find most of the proteins on our site.
Function | Related Protein |
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glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | CSGALNACT1,CHSY1,CHPF |
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity | CHPF2,CHSY1,CHPF |
metal ion binding | ITGA4,DSG1C,ZNF609A,FREM1,PCCA,ADH8A,POLA1,ZBTB48,ZFP523,ZFAT |
Interacting Protein
CHSY3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHSY3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHSY3.
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References
- Viola, M; Bartolini, B; et al. Oxidized Low Density Lipoprotein (LDL) Affects Hyaluronan Synthesis in Human Aortic Smooth Muscle Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 288:29595-29603(2013).
- Nakagawa, N; Izumikawa, T; et al. Sulfation of glucuronic acid in the linkage tetrasaccharide by HNK-1 sulfotransferase is an inhibitory signal for the expression of a chondroitin sulfate chain on thrombomodulin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 415:109-113(2011).