CHSY3

  • Official Full Name

    chondroitin sulfate synthase 3
  • Synonyms

    CHSY3;chondroitin sulfate synthase 3;24293;ENSG00000198108;CSS3;CHSY2;5q23.3;chondroitin sulfate synthase 3;chondroitin sulfate synthase 3;chSy-2;chondroitin synthase 2;chondroitin synthase-2;carbohydrate synthase 2;N-acetylgalactosaminyltransferase 3;chondroitin glucuronyltransferase 3;N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3;glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II;EC 2.4.1.175 EC 2.4.1.226

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHSY3-11236H Recombinant Human CHSY3, His-tagged E.coli Human His 571-769a.a.
CHSY3-3459M Recombinant Mouse CHSY3 Protein Mammalian Cells Mouse His
CHSY3-5503Z Recombinant Zebrafish CHSY3 Mammalian Cells Zebrafish His
CHSY3-1680M Recombinant Mouse CHSY3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CHSY3-1680M-B Recombinant Mouse CHSY3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CHSY3-785H Recombinant Human CHSY3 Protein, His-tagged E.coli Human His Glu685-Ser882
Chsy3-786M Recombinant Mouse Chsy3 Protein, His-tagged E.coli Mouse His Ala612-Ser884

    Involved Pathway

    CHSY3 involved in several pathways and played different roles in them. We selected most pathways CHSY3 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHSY3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways LAP3,PDXKB,ATP6V0E,B4GALT6,PPCDC,PCYT1BA,NDST3,ALDH1A2,PTGES3A,CBR3
    Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate CSGALNACT1,CHST3A,CHST15,XYLT2,XYLT1,CSGALNACT2,CHPF2,CHST7,CHST3,CHST3B

    Protein Function

    CHSY3 has several biochemical functions, for example, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity,glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHSY3 itself. We selected most functions CHSY3 had, and list some proteins which have the same functions with CHSY3. You can find most of the proteins on our site.

    Function Related Protein
    glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity CSGALNACT1,CHSY1,CHPF
    N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity CHPF2,CHSY1,CHPF
    metal ion binding ITGA4,DSG1C,ZNF609A,FREM1,PCCA,ADH8A,POLA1,ZBTB48,ZFP523,ZFAT

    Interacting Protein

    CHSY3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHSY3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHSY3.

    Resources

    References

    • Viola, M; Bartolini, B; et al. Oxidized Low Density Lipoprotein (LDL) Affects Hyaluronan Synthesis in Human Aortic Smooth Muscle Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 288:29595-29603(2013).
    • Nakagawa, N; Izumikawa, T; et al. Sulfation of glucuronic acid in the linkage tetrasaccharide by HNK-1 sulfotransferase is an inhibitory signal for the expression of a chondroitin sulfate chain on thrombomodulin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 415:109-113(2011).

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