CHFR
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Official Full Name
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -
Overview
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014] -
Synonyms
CHFR;checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase;RNF116;RNF196;E3 ubiquitin-protein ligase CHFR;RING finger protein 196
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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CHFR-11171H | Recombinant Human CHFR, GST-tagged | E.coli | Human | GST | C-term-310a.a. | |
CHFR-1227H | Recombinant Human CHFR Protein, GST-Tagged | Wheat Germ | Human | GST | ||
CHFR-3389M | Recombinant Mouse CHFR Protein | Mammalian Cell | Mouse | His | ||
CHFR-5821Z | Recombinant Zebrafish CHFR | Mammalian Cell | Zebrafish | His | ||
CHFR-0422H | Recombinant Human CHFR Protein (E2-N664), Tag Free | E.coli | Human | Non | E2-N664 | |
CHFR-0423H | Recombinant Human CHFR Protein (E2-N664), His tagged | E.coli | Human | His | E2-N664 | |
CHFR-1638M | Recombinant Mouse CHFR Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi | ||
CHFR-1638M-B | Recombinant Mouse CHFR Protein Pre-coupled Magnetic Beads | HEK293 | Mouse | |||
Chfr-2142M | Recombinant Mouse Chfr Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK | ||
CHFR-3191HF | Recombinant Full Length Human CHFR Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 652 amino acids | |
CHFR-3218H | Recombinant Human CHFR Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
Involved Pathway
CHFR involved in several pathways and played different roles in them. We selected most pathways CHFR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHFR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
CHFR has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CHFR itself. We selected most functions CHFR had, and list some proteins which have the same functions with CHFR. You can find most of the proteins on our site.
Function | Related Protein |
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Interacting Protein
CHFR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHFR here. Most of them are supplied by our site. Hope this information will be useful for your research of CHFR.
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References