CER1
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Official Full Name
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) -
Overview
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. -
Synonyms
CER1;cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis);cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily);cerberus;DAND4;CER 1;CER1_HUMAN;Cerberus 1;Cerberus 1 cysteine knot superfamily homolog (Xenopus laevis);Cerberus related 1;Cerberus related protein;Cerberus-related protein;Cerberus1;DAN domain family member 4;DAND 4;MGC119894;MGC119895;MGC96951;OTTHUMP00000022757;cerberus-related 1
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- E.coli
- Mammalian cells
- Wheat Germ
- Insect Cell
- Mammalian Cell
- HEK293
- Human Cell
- In Vitro Cell Free System
- GST
- His
- Fc
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CER1-11121H | Recombinant Human CER1, GST-tagged | E.coli | Human | GST | 1-267a.a. | |
| CER1-3331H | Recombinant Human CER1 protein, His-tagged | E.coli | Human | His | 18-180 aa | |
| Cer1-226M |
Active Recombinant Mouse Cer1, Met-tagged
|
E.coli | Mouse | 18-272 a.a. |
|
|
| CER1-878C |
Active Recombinant Chicken CER1 Protein, Fc Chimera
|
Mammalian cells | Chicken | Fc |
|
|
| CER1-1144H | Recombinant Human CER1 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
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| CER1-250H | Recombinant Human CER1 Protein, His-tagged | Insect Cell | Human | His | 1-267 a.a. |
|
| CER1-6386C | Recombinant Chicken CER1 | Mammalian Cell | Chicken | His |
|
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| CER1-7775H | Recombinant Human CER1, His-tagged | HEK293 | Human | His |
|
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| CER1-821R | Recombinant Rhesus monkey CER1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CER1-338HCL | Recombinant Human CER1 cell lysate | Human | Non |
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| CER1-114H | Recombinant Human CER1 Protein, His-tagged | Human Cell | Human | His | 279-390 a.a. |
|
| CER1-1603H | Recombinant Human CER1 Protein (Thr18-Ala267), C-His tagged | Mammalian cells | Human | His | Thr18-Ala267 |
|
| CER1-3245HF | Recombinant Full Length Human CER1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 267 amino acids |
|
| CER1-647R | Recombinant Rhesus Macaque CER1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CER1-647R-B | Recombinant Rhesus Macaque CER1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
Involved Pathway
CER1 involved in several pathways and played different roles in them. We selected most pathways CER1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CER1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | SIAH1A,RBX1,PRKACAA,PPP3R1,CACYBP,WNT2,MAPK8B,AXIN1,TCF7,WIF1 |
Protein Function
CER1 has several biochemical functions, for example, BMP binding,cytokine activity,morphogen activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CER1 itself. We selected most functions CER1 had, and list some proteins which have the same functions with CER1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | BMP5,TNFSF9,EDN1,IFNA17,NDR1,IL21,GREM2,IL22,LTB,CMTM2B |
| morphogen activity | DAND5,Shh,GREM1,NODAL,NBL1 |
| protein homodimerization activity | DMRTC2,PKD2,ARID3A,TIRAP,IKZF2,RAB11FIP4B,SRR,MYH7,TRIM5,C6orf108 |
| BMP binding | BMPR2,NBL1,GDF5,GREM2,GREM1,TCAP,HFE2 |
Interacting Protein
CER1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CER1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CER1.
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