CEP170
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Official Full Name
centrosomal protein 170kDa -
Overview
The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. -
Synonyms
CEP170;centrosomal protein 170kDa;KIAA0470;centrosomal protein of 170 kDa;FAM68A;KAB;KARP 1 binding protein;XRCC5 binding protein;KARP-1-binding protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CEP170-2649H | Recombinant Human CEP170 protein, His-tagged | E.coli | Human | His | 1012-1202 aa |
Involved Pathway
CEP170 involved in several pathways and played different roles in them. We selected most pathways CEP170 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CEP170 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CEP170 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CEP170 itself. We selected most functions CEP170 had, and list some proteins which have the same functions with CEP170. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CEP170 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CEP170 here. Most of them are supplied by our site. Hope this information will be useful for your research of CEP170.
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