CENPC1
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Official Full Name
centromere protein C 1 -
Overview
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. -
Synonyms
CENPC1;centromere protein C 1;CENP C;CENPC;hcp 4;MIF2;Centromere autoantigen C1;ICEN7;CENP-C 1;OTTHUMP00000218847;centromere autoantigen C;interphase centromere complex protein 7;hcp-4;CENP-C
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CENPC1-11094H | Recombinant Human CENPC1, GST-tagged | E.coli | Human | GST | 598-943a.a. | |
| CENPC1-3283M | Recombinant Mouse CENPC1 Protein | Mammalian Cell | Mouse | His |
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| CENPC1-7585HCL | Recombinant Human CENPC1 293 Cell Lysate | HEK293 | Human | Non |
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| CENPC1-1577M | Recombinant Mouse CENPC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CENPC1-1577M-B | Recombinant Mouse CENPC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
CENPC1 involved in several pathways and played different roles in them. We selected most pathways CENPC1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Anaphase | CENPN,ANKLE2,NUDC,VRK1,MLF1IP,ZWINT,DSN1,SGOL2,CENPH,CENPP |
| Cell Cycle, Mitotic | DSN1,CKAP5,NUF2,GINS1,RANGAP1B,NDEL1A,TCTN2,CEP72,NUP35,NSL1 |
| Chromosome Maintenance | POT1,CENPW,APITD1,OIP5,MIS18A,CENPO,NPM1,TERF2IP,SMARCA5,MIS18BP1 |
| Cell cycle | CCND1,CEP76,DPF1,NCAPG2,CSNK2A1,NCAPH,NIPBLB,GMNN,NCAPH2,MCM2 |
| Mitotic Prometaphase | SMC2,SGOL1,CENPO,KNTC1,CENPK,NSL1,CENPH,WAPAL,DSN1,ERCC6L |
| Deposition of new CENPA-containing nucleosomes at the centromere | CENPL,MIS18A,CENPQ,CENPN,CENPW,RBBP7,RBBP4,APITD1,CENPI,CENPK |
| Mitotic Metaphase and Anaphase | MLF1IP,LEMD3,CENPQ,VRK2,CDCA8,CENPO,CENPI,CENPN,ZWINT,ANKLE2 |
| M Phase | CENPP,NEK9,SGOL2,ANKLE2,GORASP1,CTDNEP1,SMC2,VRK1,GOLGA2,MAU2 |
Protein Function
CENPC1 has several biochemical functions, for example, DNA binding,centromeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPC1 itself. We selected most functions CENPC1 had, and list some proteins which have the same functions with CENPC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| centromeric DNA binding | CENPB,MLH3,MSH3,KIF2C,ZW10,MSH2 |
| DNA binding | BRPF1,HIST1H2BL,ZNF227,ARNTL2,HOXB5A,HIST1H4C,RAD50,ZBTB17,DICER1,ZFP653 |
Interacting Protein
CENPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPC1.
MIS12;DAXX;ZWINT;TCEB1;MAPK14;q9wmx2-pro_0000037551;NUP153;JAK3;CENPQ;Kif2c;CENPO;Cenph;RAD21;SGOL1;POGZ;AURKB
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