CELSR3

  • Official Full Name

    cadherin, EGF LAG seven-pass G-type receptor 3

  • Overview

    The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

  • Synonyms

    CELSR3;cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila);cadherin EGF LAG seven pass G type receptor 3, flamingo (Drosophila) homolog , EGFL1;cadherin EGF LAG seven-pass G-type receptor 3;CDHF11;FMI1;HFMI1;MEGF2;anchor

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • His
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CELSR3-474H Recombinant Human CELSR3 Protein, His-tagged E.coli Human His Ser1181~Cys1421
Celsr3-475M Recombinant Mouse Celsr3 Protein, His-tagged E.coli Mouse His Val942~Ser1175
CELSR3-1110H Recombinant Human CELSR3 Protein, GST-Tagged Wheat Germ Human GST
CELSR3-1332R Recombinant Rat CELSR3 Protein Mammalian Cell Rat His
CELSR3-3279M Recombinant Mouse CELSR3 Protein Mammalian Cell Mouse His
CELSR3-1573M Recombinant Mouse CELSR3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CELSR3-1573M-B Recombinant Mouse CELSR3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CELSR3-990R Recombinant Rat CELSR3 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
CELSR3-990R-B Recombinant Rat CELSR3 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    CELSR3 involved in several pathways and played different roles in them. We selected most pathways CELSR3 participated on our site, such as GPCRs, Other,Non-odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with CELSR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCRs, Other VN1R1,PROKR2,VMN1R49,VMN1R48,GPR61,GPR17,GPR56,VMN1R40,GPR183,GPR143
    Non-odorant GPCRs CELSR1,BAI2,GPR15,GPR132,OPN3,EMR4,O3far1,RRH

    Protein Function

    CELSR3 has several biochemical functions, for example, G-protein coupled receptor activity,calcium ion binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CELSR3 itself. We selected most functions CELSR3 had, and list some proteins which have the same functions with CELSR3. You can find most of the proteins on our site.

    Function Related Protein
    signal transducer activity PLCD3,CBLC,MRGPRA5,TAAR12I,FAM126A,OPN4XA,TAS2R113,PTGER1C,AVP,GPR21
    transmembrane signaling receptor activity CLEC2H,FZD8B,FZD7A,TLR2-2,CR2,TLR18,TNFRSF10C,TNFRSF8,OR103-4,IL1R1
    G-protein coupled receptor activity VALOPB,CCR10,QRFPR,PTGER4A,OLFR151,GPR78,CCR6A,GRM1,NMUR2,S1PR4
    calcium ion binding ANXA5,CABP1B,ANXA3,NELL1,CRELD2,TPT1,CETN3,TNNC1A,ADAM8,PCDHGC5

    Interacting Protein

    CELSR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CELSR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CELSR3.

    Csf1

    Resources

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