CDK17
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Official Full Name
cyclin-dependent kinase 17 -
Overview
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. -
Synonyms
CDK17;cyclin-dependent kinase 17;PCTAIRE protein kinase 2 , PCTK2;PCTAIRE2;PCTAIRE-motif protein kinase 2;cell division protein kinase 17;protein kinase cdc2-related PCTAIRE-2;serine/threonine-protein kinase PCTAIRE-2;PCTK2
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Zebrafish
- Mammalian Cell
- Sf9 Insect Cell
- HEK293
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CDK17 involved in several pathways and played different roles in them. We selected most pathways CDK17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDK17 has several biochemical functions, for example, ATP binding,cyclin-dependent protein serine/threonine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK17 itself. We selected most functions CDK17 had, and list some proteins which have the same functions with CDK17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cyclin-dependent protein serine/threonine kinase activity | CDK8,CDK5R1,CDK1,CDK2,CDKL4,PFTK1,CDKL3,CDK10,CCNK,ICK |
| protein binding | SF3A3,RMI1,MAP1S,KIF7,ALX1,CYBB,PSMD14,XAGE3,SCHIP1,CYGB |
| ATP binding | AK7,YARS2,PEBP1,FDXACB1,HK1,MYH15,MAT2AL,EIF2AK1,MLH1,CAMKK1A |
| protein kinase activity | IGF1RA,MAPKAPK2A,EPHB4A,ACVR2AA,CSNK1G2A,ABL1,CDKL2,CDK1,TLK1B,FYNB |
Interacting Protein
CDK17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK17 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK17.
YWHAG;Dlg4;Cdk1;YWHAZ;PRKACG;EPHA2;PTBP3;GAPDH;PTMA;YWHAB;PPP2CB;PPP2R2A;TDRD7;NOP10
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References
- Hsieh, R; Firmiano, A; et al. Expression of p16 protein in acral lentiginous melanoma. INTERNATIONAL JOURNAL OF DERMATOLOGY 48:1303-1307(2009).
- Martin, NG; McAndrew, PC; et al. Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases. FEBS JOURNAL 275:3099-3109(2008).
