CDK13
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Official Full Name
cyclin-dependent kinase 13 -
Overview
The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described. -
Synonyms
CHED;CDC2L;CDC2L5;hCDK13;FLJ35215;KIAA1791;cyclin-dependent kinase 13;OTTHUMP00000159007;OTTHUMP00000159008;CDC2-related protein kinase 5;cell division protein kinase 13;cell division cycle 2-like protein kinase 5;cholinesterase-related cell division controller
Recombinant Proteins
- Human
- Mouse
- Insect Cell
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDK13-01H | Recombinant Human CDK13/Cyclin K protein, GST-tagged | Insect Cell | Human | GST | CDK13 (516-end) and Cyclin K (Full Length) |
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| CDK13-02H | Recombinant Human CDK13 protein, GST-tagged | Insect Cell | Human | GST | 516-end a.a. |
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| CDK13-3193M | Recombinant Mouse CDK13 Protein | Mammalian Cell | Mouse | His |
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| CDK13-5137H | Recombinant Human CDK13 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CDK13-321HCL | Recombinant Human CDK13 cell lysate | Human | Non |
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| CDK13-08H | Recombinant Active Human CDK13/Cyclin K Complex Protein, GST-tagged | Insect Cell | Human | GST | 516-end a.a. |
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| CDK13-1516M | Recombinant Mouse CDK13 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CDK13-1516M-B | Recombinant Mouse CDK13 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CDK13-3756HF | Recombinant Full Length Human CDK13 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 324 amino acids |
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| CDK13-724H | Recombinant Human CDK13 Protein, His-tagged | E.coli | Human | His | Phe705-Leu998 |
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Involved Pathway
CDK13 involved in several pathways and played different roles in them. We selected most pathways CDK13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDK13 has several biochemical functions, for example, ATP binding,RNA polymerase II carboxy-terminal domain kinase activity,cyclin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK13 itself. We selected most functions CDK13 had, and list some proteins which have the same functions with CDK13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | NEK4,XRCC6,KIF23,PSTK,DDX4,MYO19,PKN1,PHKG2,KIF20B,CAMKK2 |
| RNA polymerase II carboxy-terminal domain kinase activity | CCNK,CDK8,CDK1,MAPK1,CDK9,CDK12,CDK7 |
| cyclin binding | MDFIC,CUL3,PTCH1,CDKN1A,CDK2,HDAC3,PFTK1,FBXW7,CDK14,USP2 |
| protein binding | FAM123A,NAA38,DCP1B,RPS19,MTAP,ISCU,VAV2,ASH2L,YIPF2,RLN3 |
| cyclin-dependent protein serine/threonine kinase activity | CDK19,CDK18,CDKL3,CDK5R1,CDK1,CDK17,NAT1,CDKL1,CDK11A,CDK3 |
| protein kinase activity | CDKL5,PLK1,TAOK1,ACVR1,MAP3K2,NEK4,CSNK1G2B,CAMK2B1,LIMK1,CAMK1GA |
| poly(A) RNA binding | RPL26L1,PRPF38B,CANX,SF3A1,ZFP36,SRRT,FAM46A,GNL3,RPS21,DDX39A |
Interacting Protein
CDK13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK13.
CDK4;CDK2;CDC37;PRPF40A;imatinib;npm_alk;Lck;CDK1;EEF2;ARRB2;CCT3
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References
- Chu, J; Li, JG; et al. The Influence of 5-Lipoxygenase on Alzheimer's Disease-Related Tau Pathology: In Vivo and In Vitro Evidence. BIOLOGICAL PSYCHIATRY 74:321-328(2013).
- Lotan, Y; Bagrodia, A; et al. Prospective Evaluation of a Molecular Marker Panel for Prediction of Recurrence and Cancer-specific Survival After Radical Cystectomy. EUROPEAN UROLOGY 64:465-471(2013).
