CDK10
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Official Full Name
cyclin-dependent kinase 10 -
Overview
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CDK10;cyclin-dependent kinase 10;cyclin dependent kinase (CDC2 like) 10;PISSLRE;CDC2-related protein kinase;cell division protein kinase 10;cyclin-dependent kinase (CDC2-like) 10;cyclin-dependent kinase related protein;serine/threonine protein kin
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDK10-11045H | Recombinant Human CDK10, His-tagged | E.coli | Human | His | 1-283a.a. | |
| CDK10-0999H | Recombinant Human CDK10 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CDK10-2393Z | Recombinant Zebrafish CDK10 | Mammalian Cells | Zebrafish | His |
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| CDK10-3765C | Recombinant Chicken CDK10 | Mammalian Cells | Chicken | His |
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| CDK10-326HCL | Recombinant Human CDK10 cell lysate | Human | Non |
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| Cdk10-2084M | Recombinant Mouse Cdk10 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| CDK10-3144H | Recombinant Human CDK10 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| CDK10-3177HF | Recombinant Full Length Human CDK10 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 331 amino acids |
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| CDK10-645H | Recombinant Human CDK10 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
CDK10 involved in several pathways and played different roles in them. We selected most pathways CDK10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDK10 has several biochemical functions, for example, ATP binding,cyclin-dependent protein serine/threonine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK10 itself. We selected most functions CDK10 had, and list some proteins which have the same functions with CDK10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | LUZP4,INTS5,RWDD2B,PFKM,NECAB2,KLF5,FASTK,RTN3,FAM158A,PLXND1 |
| cyclin-dependent protein serine/threonine kinase activity | CDKL3,CDK7,CDK15,MOK,CDK14,CDK12,CDK5R1,NAT1,CDK20,CCNK |
| ATP binding | PRKCB,ROCK2A,TXK,MYH9,MAT2AA,DHX9,CCT8,MAP3K4,MCM5,ALK |
Interacting Protein
CDK10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK10 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK10.
PIN1;HSP90AB1;ETS2;SEMG2;Pin1;raf1_human_gene;Wdr48;PRKD2
Resources
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References
- Ehrenschwender, M; Bittner, S; et al. XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis. CELL DEATH & DISEASE 5:-(2014).
- Zhu, BT; Xiahou, ZK; et al. MTHFR promotes heterochromatin maintenance. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 447:702-706(2014).
