CDH19
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Official Full Name
cadherin 19, type 2 -
Overview
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. -
Synonyms
CDH19;cadherin 19, type 2;cadherin-19;CDH7;UNQ478;CDH 19;CDH7L2;PRO941
Recombinant Proteins
- Human
- Chicken
- E.coli
- N-MBP-Flag
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDH19-11035H | Recombinant Human CDH19, GST-tagged | E.coli | Human | GST | 1-390a.a. | |
| CDH19-3719H | Recombinant Human CDH19 protein, His-tagged | E.coli | Human | His | 1-390 aa | |
| CDH19-1413H |
Recombinant Human CDH19 protein, MBP-Flag-tagged
|
N-MBP-Flag | Human | Gly44-His569 |
|
|
| CDH19-332H | Recombinant Human CDH19 protein, GST-tagged | Wheat Germ | Human | GST | 1-772 a.a. |
|
| CDH19-3728C | Recombinant Chicken CDH19 | Mammalian Cell | Chicken | His |
|
|
| CDH19-325HCL | Recombinant Human CDH19 cell lysate | Human | Non |
|
||
| CDH19-694HF | Recombinant Full Length Human CDH19 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 772 amino acids |
|
Involved Pathway
CDH19 involved in several pathways and played different roles in them. We selected most pathways CDH19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDH19 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH19 itself. We selected most functions CDH19 had, and list some proteins which have the same functions with CDH19. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | MYL13,DLC,OTOFA,PLS1,VWCE,EFEMP2,MYLZ3,AP1S2,JAG2,SDF4 |
Interacting Protein
CDH19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH19 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH19.
Resources
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References
- Cui, B; Zhang, SP; et al. Targeting ROR1 Inhibits Epithelial-Mesenchymal Transition and Metastasis. CANCER RESEARCH 73:3649-3660(2013).
- Davidov, T; Nagar, M; et al. Carbonic anhydrase 4 and crystallin alpha-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology. JOURNAL OF SURGICAL RESEARCH 190:565-574(2014).
