CDC42EP1
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Official Full Name
CDC42 effector protein (Rho GTPase binding) 1 -
Overview
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. -
Synonyms
CDC42EP1;CDC42 effector protein (Rho GTPase binding) 1;cdc42 effector protein 1;55 kDa bone marrow stromal/endothelial cell protein;Borg5;CEP1;MSE55;serum constituent protein;Binder of Rho GTPases 5;BORG 5;BORG5_HUMAN;CEP 1;MGC15316;MSE 55;OTTHUMP00000028709;Serum protein MSE55;OTTHUMP00000197884
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CDC42EP1 involved in several pathways and played different roles in them. We selected most pathways CDC42EP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC42EP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDC42EP1 has several biochemical functions, for example, GTP-Rho binding,GTPase activator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC42EP1 itself. We selected most functions CDC42EP1 had, and list some proteins which have the same functions with CDC42EP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ISG15,ACY3,SNX32,HACE1,MYO10,ERAP1,SPRY1,PROM1,GMCL1P1,RNF139 |
| GTPase activator activity | TBC1D22B,TBC1D20,TBCD,DAB2IPB,ARHGAP4A,ARHGEF12,AXIN2,ACAP1,TBC1D9B,RAB3GAP1 |
| GTP-Rho binding | TNFAIP1,ROCK2B,ROCK2A,PKN1,CDC42EP5,CDC42EP4A,EXOC1,RTKN,NET1,CDC42EP1B |
Interacting Protein
CDC42EP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC42EP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC42EP1.
CDC42;RHOJ;DEF6;MDFI;PLSCR1;FHL3;RBPMS;MAPKAP1;KRTAP4-12;PTBP3
Resources
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References
- Awasthi, YC; Sharma, R; et al. The non-ABC drug transporter RLIP76 (RALBP-1) plays a major role in the mechanisms of drug resistance. CURRENT DRUG METABOLISM 8:315-323(2007).
- Wang, YQ; Ohkubo, T; et al. Enhanced cell-substratum adhesion of E-cadherin-expressing cells is mediated by activation of the small GTPase protein, Rac1. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 17:637-642(2006).
