CD2BP2
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Official Full Name
CD2 (cytoplasmic tail) binding protein 2 -
Overview
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. -
Synonyms
CD2BP2;CD2 (cytoplasmic tail) binding protein 2;CD2 antigen (cytoplasmic tail) binding protein 2;CD2 antigen cytoplasmic tail-binding protein 2;LIN1;PPP1R59;protein phosphatase 1;regulatory subunit 59;Snu40;FWP010;U5 snRNP 52K protein;CD2 cytoplasmic domain-binding protein 2;protein phosphatase 1, regulatory subunit 59;U5-52K
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CD2BP2-0775H | Recombinant Human CD2BP2 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CD2BP2-11196Z | Recombinant Zebrafish CD2BP2 | Mammalian Cell | Zebrafish | His |
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| CD2BP2-3070M | Recombinant Mouse CD2BP2 Protein | Mammalian Cell | Mouse | His |
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| CD2BP2-735R | Recombinant Rhesus monkey CD2BP2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CD2BP2-175HCL | Recombinant Human CD2BP2 lysate | HEK293 | Human | Non |
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| CD2BP2-1450M | Recombinant Mouse CD2BP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CD2BP2-1450M-B | Recombinant Mouse CD2BP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CD2BP2-3097HF | Recombinant Full Length Human CD2BP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 341 amino acids |
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| CD2BP2-561R | Recombinant Rhesus Macaque CD2BP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CD2BP2-561R-B | Recombinant Rhesus Macaque CD2BP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
CD2BP2 involved in several pathways and played different roles in them. We selected most pathways CD2BP2 participated on our site, such as Gene Expression,Processing of Capped Intron-Containing Pre-mRNA,mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD2BP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Processing of Capped Intron-Containing Pre-mRNA | PDCD7,HNRNPA0B,U2AF2,HNRNPH1,PCBP2,TXNL4A,WTAP,HNRNPH1L,HNRNPUL1,HNRNPR |
| mRNA Splicing | HNRNPH1L,HNRNPA0B,RBM5,HNRNPF,SFRS3A,HNRNPH2,TTC6,PRPF8,HNRNPL2,HNRNPA0 |
| mRNA processing | SNRPN,ZFP346,ZFML,CELF2,CELF4,RPL36A-HNRNPH2,HNRNPR,SFPQ,SREK1,Ankar |
| Gene Expression | HNRNPL,TAF1C,HNRNPH1,PAPOLA,MAEL,ZNF157,QTRT1,ZNF334,EIF2B1,ZMAT5 |
| mRNA Splicing - Major Pathway | PRPF8,HNRNPA2B1,HNRPL,SUGP1,HNRNPL2,PTBP1B,HNRNPH2,HNRNPF,YBX1,HNRNPD |
Protein Function
CD2BP2 has several biochemical functions, for example, protein binding,ribonucleoprotein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD2BP2 itself. We selected most functions CD2BP2 had, and list some proteins which have the same functions with CD2BP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ribonucleoprotein complex binding | ITCH,SRP54A,TIMM50,PES1,WDR12,SRP54,CKAP5,SECISBP2,PRPF31,UHMK1 |
| protein binding | EDC3,CDC42BPA,S100P,POU5F1,PTPRR,HER5,PAK6,CELSR1,FHL2,BIN2 |
Interacting Protein
CD2BP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD2BP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD2BP2.
CD2;PRPF6
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