CBX2
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Official Full Name
chromobox homolog 2 -
Overview
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010] -
Synonyms
CBX2;chromobox homolog 2;M33;CDCA6;SRXY5;chromobox protein homolog 2;modifier 3;Pc class homolog;cell division cycle associated 6;chromobox homolog 2 (Pc class homolog, Drosophila)
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CBX2-10767H | Recombinant Human CBX2, His-tagged | E.coli | Human | His | 1-211a.a. | |
| CBX2-0479H | Recombinant Human CBX2 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CBX2-2792M | Recombinant Mouse CBX2 Protein | Mammalian Cell | Mouse | His |
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| CBX2-9724Z | Recombinant Zebrafish CBX2 | Mammalian Cell | Zebrafish | His |
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| CBX2-7806HCL | Recombinant Human CBX2 293 Cell Lysate | HEK293 | Human | Non |
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| CBX2-1271M | Recombinant Mouse CBX2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CBX2-1271M-B | Recombinant Mouse CBX2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CBX2-2779HF | Recombinant Full Length Human CBX2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 211 amino acids |
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Involved Pathway
CBX2 involved in several pathways and played different roles in them. We selected most pathways CBX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CBX2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CBX2 itself. We selected most functions CBX2 had, and list some proteins which have the same functions with CBX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CBX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX2.
BMI1;MDFI;386677;KRTAP2-3;RBMY1A1;KRTAP10-7;KRTAP10-9
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