CBR3

  • Official Full Name

    carbonyl reductase 3

  • Overview

    Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols.The enzyme is classified as a monomeric NADPH-dependent oxidoreductase.CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

  • Synonyms

    CBR3;carbonyl reductase 3;carbonyl reductase [NADPH] 3;SDR21C2;short chain dehydrogenase/reductase family 21C;member 2;Carbonyl reductase (NADPH) 3;Carbonyl reductase (NADPH) 3 EC 1.1.1.184;CBR 3;CBR3_HUMAN;EC 1.1.1.184;hCBR3;NADPH dependent carbonyl reductase 3;NADPH-dependent carbonyl reductase 3;Short chain dehydrogenase/reductase family 21C member 2;OTTHUMP00000109012;short chain dehydrogenase/reductase family 21C, member 2

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • E.coli
  • Wheat Germ
  • HEK293
  • Mammalian Cell
  • In Vitro Cell Free System
  • HEK293T
  • Mamanlian cells
  • GST
  • His
  • Myc&DDK
  • Non
  • His&Fc&Avi
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
CBR3-10763H Recombinant Human CBR3, GST-tagged E.coli Human GST 1-277a.a.
CBR3-184H Recombinant Human Carbonyl Reductase 3, His-tagged E.coli Human His
CBR3-0468H Recombinant Human CBR3 Protein, GST-Tagged Wheat Germ Human GST
CBR3-185H Recombinant Human CBR3, MYC/DDK-tagged HEK293 Human Myc&DDK
CBR3-199H Recombinant Human CBR3, His tagged E.coli Human Non 1-277 a.a.
CBR3-26328TH Recombinant Human CBR3, His-tagged E.coli Human His 277 amino acids
CBR3-2788M Recombinant Mouse CBR3 Protein Mammalian Cell Mouse His
CBR3-644R Recombinant Rhesus monkey CBR3 Protein, His-tagged Mammalian Cell Rhesus macaque His
CBR3-7810HCL Recombinant Human CBR3 293 Cell Lysate HEK293 Human Non
CBR3-1268M Recombinant Mouse CBR3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CBR3-1268M-B Recombinant Mouse CBR3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CBR3-2774HF Recombinant Full Length Human CBR3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 277 amino acids
Cbr3-440M Recombinant Mouse Cbr3 Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
CBR3-472R Recombinant Rhesus Macaque CBR3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
CBR3-472R-B Recombinant Rhesus Macaque CBR3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
CBR3-8695HFL Recombinant Full Length Human CBR3, Flag-tagged Mamanlian cells Human Flag Full L.

    Involved Pathway

    CBR3 involved in several pathways and played different roles in them. We selected most pathways CBR3 participated on our site, such as Arachidonic acid metabolism,Metabolism of xenobiotics by cytochrome P,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways PTDSS1A,CMPK,POLR2J2,PIGH,ATP6V1B2,GCSHB,PAICS,C1GALT1A,AGPAT5,CD38
    Arachidonic acid metabolism CYP4A11,PLA2G4AA,PLA2G4F,PLA2G4A,ALOX12E,CYP2AD3,CYP4F18,CYP2C37,CYP2C70,FAAH2B
    Metabolism of xenobiotics by cytochrome P UGT2B15,GSTA3,CYP2F2,MGST3,MGST1.2,GSTM2,UGT5G1,GSTA1,GSTO1,CBR1L

    Protein Function

    CBR3 has several biochemical functions, for example, 3-keto sterol reductase activity,NADPH binding,carbonyl reductase (NADPH) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CBR3 itself. We selected most functions CBR3 had, and list some proteins which have the same functions with CBR3. You can find most of the proteins on our site.

    Function Related Protein
    carbonyl reductase (NADPH) activity CBR2,DHRS4,DHRS2,CBR1
    NADPH binding CRYZ,GRHPR,DHFR,TP53I3,CBR4,KCNAB1,FASN,HMGCR,MTRR,DECR1
    3-keto sterol reductase activity HSD17B7,DHRS4

    Interacting Protein

    CBR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBR3.

    SGK1;USP3;ARIH2;RAB35;GABARAP;LDLR;CBR1;MKI67;RPS10;CCNL2;GABARAPL1

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All CBR3 Products

    Required fields are marked with *

    My Review for All CBR3 Products

    Required fields are marked with *