CARD6
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Official Full Name
caspase recruitment domain family, member 6 -
Overview
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. -
Synonyms
CARD6;caspase recruitment domain family, member 6;caspase recruitment domain-containing protein 6;CINCIN1;caspase recruitment domain protein 6;CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CARD6-0395H | Recombinant Human CARD6 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
Involved Pathway
CARD6 involved in several pathways and played different roles in them. We selected most pathways CARD6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CARD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CARD6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CARD6 itself. We selected most functions CARD6 had, and list some proteins which have the same functions with CARD6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CARD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CARD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CARD6.
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References
- Prescimone, T; D'Amico, A; et al. Caspase-1 transcripts in failing human heart after mechanical unloading. CARDIOVASCULAR PATHOLOGY 24:11-18(2015).
- Block, MS; Charbonneau, B; et al. Variation in NF-kappa B Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:1421-1427(2014).
