CALHM1
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Official Full Name
calcium homeostasis modulator 1 -
Overview
This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimers disease in some populations, but the pathogenicity of this polymorphism is unclear. -
Synonyms
CALHM1;calcium homeostasis modulator 1;FAM26C, family with sequence similarity 26, member C;calcium homeostasis modulator protein 1;CAHM1_HUMAN;FAM26C;Family with sequence similarity 26, member C;MGC39514;MGC39617;OTTHUMP00000020413;Protein FAM26C
Recombinant Proteins
- Human
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- E.coli
- Non
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CALHM1-0302H | Recombinant Human CALHM1 Protein | Wheat Germ | Human | Non |
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| CALHM1-1130H | Recombinant Human CALHM1 | Mammalian Cells | Human | His |
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| CALHM1-7892HCL | Recombinant Human CALHM1 293 Cell Lysate | HEK293 | Human | Non |
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| CALHM1-2584H | Recombinant Human CALHM1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| CALHM1-2584H-B | Recombinant Human CALHM1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| CALHM1-3062HF | Recombinant Full Length Human CALHM1 Protein | In Vitro Cell Free System | Human | Full L. 275 amino acids |
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| RFL1183HF | Recombinant Full Length Human Calcium Homeostasis Modulator Protein 1(Calhm1) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-346) |
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Involved Pathway
CALHM1 involved in several pathways and played different roles in them. We selected most pathways CALHM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CALHM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CALHM1 has several biochemical functions, for example, calcium activated cation channel activity,identical protein binding,voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CALHM1 itself. We selected most functions CALHM1 had, and list some proteins which have the same functions with CALHM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated ion channel activity | TRPM5,CACNA2D3,KCNK7,CACNA1C,KCNC2,CX35B,KCNK16,CACNA1SA,KCNJ16,KCNIP1 |
| calcium activated cation channel activity | TRPM4A,CATSPER2,TRPM4,TRPM5,TRPM4C,ANO6,TMEM63C,CATSPER1,ANO10,PKD2L1 |
| identical protein binding | DYRK1A,CHEK2,ZDHHC17,CCDC91,HGF,RUVBL2,DES,REG3B,TRIM55,ERBB2 |
| voltage-gated calcium channel activity | CACNG1A,TMC1,RYR1,CACNA2D1,NCS1,CACNA1DA,CACNA1SA,TPCN2,CACNA2D4,CACNG4 |
Interacting Protein
CALHM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALHM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CALHM1.
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