CABLES1

  • Official Full Name

    Cdk5 and Abl enzyme substrate 1

  • Overview

    This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

  • Synonyms

    CABLES1;Cdk5 and Abl enzyme substrate 1;CABL1;IK3-1;CABLES;HsT2563;CDK5 and ABL1 enzyme substrate 1;interactor with CDK3 1
Cat.# Product name Source (Host) Species Tag Protein Length Price
CABLES1-1361H Active Recombinant Human ABL1, GST-tagged Sf9 Insect Cell Human GST 27 aa-end
CABLES1-0256H Recombinant Human CABLES1 Protein, GST-Tagged Wheat Germ Human GST
CABLES1-6024Z Recombinant Zebrafish CABLES1 Mammalian Cell Zebrafish His
CABLES1-267HCL Recombinant Human CABLES1 cell lysate Human Non
CABLES1-2263H Recombinant Human CABLES1 Protein, His-tagged E.coli Human His
CABLES1-2762HF Recombinant Full Length Human CABLES1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 368 amino acids

    Involved Pathway

    CABLES1 involved in several pathways and played different roles in them. We selected most pathways CABLES1 participated on our site, such as Factors involved in megakaryocyte development and platelet production,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CABLES1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hemostasis RAPGEF3,HBE1,BRPF3,CEACAM8,BA1L,SLC7A10,PROCA,MERTK,SLC8A2A,MYB
    Factors involved in megakaryocyte development and platelet production KIF3B,HBG1,CENPE,EHD1,KIF26A,DOCK9,KIF18A,KIF2A,MFN1,KIF2C

    Protein Function

    CABLES1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CABLES1 itself. We selected most functions CABLES1 had, and list some proteins which have the same functions with CABLES1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding MRPL49,RITA1,C3orf52,C14orf118,TRPC2,LSM3,MTMR7,TRIM37,FAM162A,BPIFA2

    Interacting Protein

    CABLES1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CABLES1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CABLES1.

    CDK5;TP63;TP53;ALB

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