C8B
-
Official Full Name
complement component 8, beta polypeptide -
Overview
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection. -
Synonyms
C8B;complement component 8, beta polypeptide;complement component C8 beta chain;complement component 8 subunit beta;MGC163447
Recombinant Proteins
- Rat
- Human
- Mouse
- Zebrafish
- Mammalian Cell
- E.coli
- HEK293
- Mammalian cells
- HEK293T
- His
- His&T7
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
- His&Myc
Involved Pathway
C8B involved in several pathways and played different roles in them. We selected most pathways C8B participated on our site, such as Complement and coagulation cascades,Prion diseases,Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Prion diseases | STIP1,C8G,MAP2K2,LAMC1,SOD1,MAP2K1,FYN,C1QA,IL6,MAPK3 |
| Systemic lupus erythematosus | H2AFB2,HIST1H2AA,HIST1H2BG,CD28,CD40,SNRPD1,HIST1H4D,HIST1H2AP,HIST1H4N,HLA-DOB |
| Complement and coagulation cascades | SERPINE1,F13A1,CR1,C1QC,CFI,PROS1,FGA,F7,MASP1,PLAT |
| Amoebiasis | TLR2,Itgam&Itgb2,IL12A,CXCL8,PRKACB,ITGAM,ACTN2,LAMA3,HSPB1,SERPINB4 |
Protein Function
C8B has several biochemical functions, for example, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C8B itself. We selected most functions C8B had, and list some proteins which have the same functions with C8B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | TG,GRIN2A,PCSK2,PPARA,PPP1R9B,BAG3,PPFIA2,UQCRFS1,KAT2B,GIT2 |
Interacting Protein
C8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C8B here. Most of them are supplied by our site. Hope this information will be useful for your research of C8B.
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