C17ORF70
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Official Full Name
chromosome 17 open reading frame 70 -
Overview
FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 (see MIM 227646) monoubiquitination (Ling et al., 2007 [PubMed 17396147]).[supplied by OMIM, Mar 2008] -
Synonyms
C17ORF70;chromosome 17 open reading frame 70;FAAP100;Fanconi anemia-associated protein of 100 kDa;Fanconi anemia-associated protein, 100kDa;Fanconi anemia core complex 100 kDa subunit;Fanconi anemia associated protein 100 kDa subunit
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Involved Pathway
C17ORF70 involved in several pathways and played different roles in them. We selected most pathways C17ORF70 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C17ORF70 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
C17ORF70 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C17ORF70 itself. We selected most functions C17ORF70 had, and list some proteins which have the same functions with C17ORF70. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
C17ORF70 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C17ORF70 here. Most of them are supplied by our site. Hope this information will be useful for your research of C17ORF70.
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References
- Babbs, C; Lloyd, D; et al. De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder. JOURNAL OF MEDICAL GENETICS 51:737-747(2014).
- Fennell, DA; Myrand, SP; et al. Association between Gene Expression Profiles and Clinical Outcome of Pemetrexed-Based Treatment in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Exploratory Results from a Phase II Study. PLOS ONE 9:-(2014).
