BTG2
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Official Full Name
BTG family, member 2 -
Overview
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle. -
Synonyms
BTG2;BTG family, member 2;protein BTG2;B cell translocation gene 2;MGC126063;MGC126064;nerve growth factor inducible anti proliferative;NGF inducible anti proliferative protein PC3;PC3;pheochromacytoma cell 3;TIS21;BTG family member 2;BTG2_HUMAN;NGF-inducible anti-proliferative protein PC3;OTTHUMP00000033982;pheochromacytoma cell-3;B-cell translocation gene 2;nerve growth factor-inducible anti-proliferative
Recombinant Proteins
- Human
- Rat
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- HIS
- Non
- His&Fc&Avi
Involved Pathway
BTG2 involved in several pathways and played different roles in them. We selected most pathways BTG2 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with BTG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | BTG4,EDC3,CNOT3B,C1D,EXOSC2,CNOT6,ENO1B,EDC4,TTC37,SMX5 |
Protein Function
BTG2 has several biochemical functions, for example, protein binding,transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BTG2 itself. We selected most functions BTG2 had, and list some proteins which have the same functions with BTG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MKI67,CDK13,CD36,FSCN1,CBX5,PGAP2,MAP4K5,MYBBP1A,CCDC167,NARG1 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | ATF7,ZNF148,ZFPM2,SNAI1,PITX2,PYDC3,HELT,ZBTB20,TBX15,NKX6-1 |
Interacting Protein
BTG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BTG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BTG2.
CNOT8;CNOT7;Cnot7;AR;CNOT1
Resources
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References
- Jiang, YW; Soong, TD; et al. Genome-Wide Detection of Genes Targeted by Non-Ig Somatic Hypermutation in Lymphoma. PLOS ONE 7:-(2012).
- Oliveira, RDR; Fontana, V; et al. Differential Gene Expression Profiles May Differentiate Responder and Nonresponder Patients with Rheumatoid Arthritis for Methotrexate (MTX) Monotherapy and MTX plus Tumor Necrosis Factor Inhibitor Combined Therapy. JOURNAL OF RHEUMATOLOGY 39:1524-1532(2012).
