BRE

  • Official Full Name

    brain and reproductive organ-expressed (TNFRSF1A modulator)
  • Overview

    BRCA1-A complex subunit BRE is a protein that in humans is encoded by the BRE gene.
  • Synonyms

    BRE;brain and reproductive organ-expressed (TNFRSF1A modulator);BRCA1-A complex subunit BRE;BRCA1/BRCA2 containing complex;subunit 4;BRCC4;BRCC45;BRCA1/BRCA2-containing complex subunit 45;BRCA1/BRCA2-containing complex, subunit 4;brain and reprod

Recombinant Proteins

  • Rat
  • Chicken
  • Zebrafish
  • Human
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
BRE-1013R Recombinant Rat BRE Protein Mammalian Cell Rat His
BRE-1836C Recombinant Chicken BRE Mammalian Cell Chicken His
BRE-2520Z Recombinant Zebrafish BRE Mammalian Cell Zebrafish His
BRE-335H Recombinant Human BRE Protein, GST-tagged Wheat Germ Human GST
BRE-8409HCL Recombinant Human BRE 293 Cell Lysate HEK293 Human Non
BRE-3787HF Recombinant Full Length Human BRE Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 415 amino acids
BRE-671R Recombinant Rat BRE Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
BRE-671R-B Recombinant Rat BRE Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    BRE involved in several pathways and played different roles in them. We selected most pathways BRE participated on our site, such as Cell Cycle,Cell Cycle Checkpoints,DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    DNA Repair ACTL6A,COPS7A,CETN2,KDM4B,ZNF830,PIAS3,TFPT,RNF4,RBBP8,KIAA0146
    DNA Double Strand Break Response CHEK2,TP53BP1,FAM175A,EYA4,BABAM1,KDM4B,RAD50,HTATIP,EYA2,SMARCA5
    G2/M DNA damage checkpoint THRSP,RNF168,BRCC3,UIMC1,FAM175A,BARD1,BABAM1,TP53BP1
    HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) FAM175A,KIAA0146,PPP4CA,HUS1,TOPBP1,EME2,RAD1,GEN1,TIPIN,RAD51AP1
    DNA Double-Strand Break Repair SMARCA5,POLD3,GEN1,TDP2B,THRSP,PPP4CA,RBBP8,EYA2,PPP4CB,KIAA0146
    G2/M Checkpoints RAD9B,FAM175A,HUS1,THRSP,BRCC3,BABAM1,BARD1,RAD9A,RAD1,TP53BP1
    Cell Cycle Checkpoints HIST3H2BB,TP53BP1,MCM10,BARD1,CHEK2,CHEK1,RAD50,CDK5RAP2,KAT5,RAD9A
    Cell cycle CDC45,KIF20A,MCM4,TBC1D8,DBF4,CCP110,RAD1,HTATIP,STAG2,CDC14AB

    Protein Function

    BRE has several biochemical functions, for example, peroxisome targeting sequence binding,polyubiquitin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRE itself. We selected most functions BRE had, and list some proteins which have the same functions with BRE. You can find most of the proteins on our site.

    Function Related Protein
    tumor necrosis factor receptor binding TNFSF10L4,LTA,TNF,CASP8,TNFSF10,TNFSF10L,TRADD,CD70,TRAF3,TNFSF13B
    polyubiquitin binding BRCC3,RAD18,PSMD4,AGL,RAD23A,UBQLN4,ZFAND6,DZIP3,PSMD4B,HDAC6
    protein binding CUEDC2,ISOC2,AK8,TMSB10,ING5,RALGAPA1,RAB8B,TMEM59,PRAM1,DOT1L
    peroxisome targeting sequence binding PEX5,PEX5L

    Interacting Protein

    BRE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRE here. Most of them are supplied by our site. Hope this information will be useful for your research of BRE.

    BABAM1;BRCC3;FAM175B;RPN2;SHMT2;PHB;LRPPRC;CUL1;FKBP8;ATG2A;DHRS7B;FAM175A;USP7;TTC28

    Resources

    References

    • Karamitopoulou, E; Zlobec, I; et al. Proposal for a 10-high-power-fields scoring rnethod for the assessment of tumor budding in colorectal cancer. MODERN PATHOLOGY 26:295-301(2013).
    • Lang, LX; Li, WH; et al. New Methods for Labeling RGD Peptides with Bromine-76. THERANOSTICS 1:341-353(2011).

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