BRE
-
Official Full Name
brain and reproductive organ-expressed (TNFRSF1A modulator) -
Overview
BRCA1-A complex subunit BRE is a protein that in humans is encoded by the BRE gene. -
Synonyms
BRE;brain and reproductive organ-expressed (TNFRSF1A modulator);BRCA1-A complex subunit BRE;BRCA1/BRCA2 containing complex;subunit 4;BRCC4;BRCC45;BRCA1/BRCA2-containing complex subunit 45;BRCA1/BRCA2-containing complex, subunit 4;brain and reprod
Recombinant Proteins
- Rat
- Chicken
- Zebrafish
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
BRE-1013R | Recombinant Rat BRE Protein | Mammalian Cell | Rat | His | ||
BRE-1836C | Recombinant Chicken BRE | Mammalian Cell | Chicken | His | ||
BRE-2520Z | Recombinant Zebrafish BRE | Mammalian Cell | Zebrafish | His | ||
BRE-335H | Recombinant Human BRE Protein, GST-tagged | Wheat Germ | Human | GST | ||
BRE-8409HCL | Recombinant Human BRE 293 Cell Lysate | HEK293 | Human | Non | ||
BRE-3787HF | Recombinant Full Length Human BRE Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 415 amino acids | |
BRE-671R | Recombinant Rat BRE Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi | ||
BRE-671R-B | Recombinant Rat BRE Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
Involved Pathway
BRE involved in several pathways and played different roles in them. We selected most pathways BRE participated on our site, such as Cell Cycle,Cell Cycle Checkpoints,DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
DNA Repair | ACTL6A,COPS7A,CETN2,KDM4B,ZNF830,PIAS3,TFPT,RNF4,RBBP8,KIAA0146 |
DNA Double Strand Break Response | CHEK2,TP53BP1,FAM175A,EYA4,BABAM1,KDM4B,RAD50,HTATIP,EYA2,SMARCA5 |
G2/M DNA damage checkpoint | THRSP,RNF168,BRCC3,UIMC1,FAM175A,BARD1,BABAM1,TP53BP1 |
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | FAM175A,KIAA0146,PPP4CA,HUS1,TOPBP1,EME2,RAD1,GEN1,TIPIN,RAD51AP1 |
DNA Double-Strand Break Repair | SMARCA5,POLD3,GEN1,TDP2B,THRSP,PPP4CA,RBBP8,EYA2,PPP4CB,KIAA0146 |
G2/M Checkpoints | RAD9B,FAM175A,HUS1,THRSP,BRCC3,BABAM1,BARD1,RAD9A,RAD1,TP53BP1 |
Cell Cycle Checkpoints | HIST3H2BB,TP53BP1,MCM10,BARD1,CHEK2,CHEK1,RAD50,CDK5RAP2,KAT5,RAD9A |
Cell cycle | CDC45,KIF20A,MCM4,TBC1D8,DBF4,CCP110,RAD1,HTATIP,STAG2,CDC14AB |
Protein Function
BRE has several biochemical functions, for example, peroxisome targeting sequence binding,polyubiquitin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRE itself. We selected most functions BRE had, and list some proteins which have the same functions with BRE. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
tumor necrosis factor receptor binding | TNFSF10L4,LTA,TNF,CASP8,TNFSF10,TNFSF10L,TRADD,CD70,TRAF3,TNFSF13B |
polyubiquitin binding | BRCC3,RAD18,PSMD4,AGL,RAD23A,UBQLN4,ZFAND6,DZIP3,PSMD4B,HDAC6 |
protein binding | CUEDC2,ISOC2,AK8,TMSB10,ING5,RALGAPA1,RAB8B,TMEM59,PRAM1,DOT1L |
peroxisome targeting sequence binding | PEX5,PEX5L |
Interacting Protein
BRE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRE here. Most of them are supplied by our site. Hope this information will be useful for your research of BRE.
BABAM1;BRCC3;FAM175B;RPN2;SHMT2;PHB;LRPPRC;CUL1;FKBP8;ATG2A;DHRS7B;FAM175A;USP7;TTC28
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References
- Karamitopoulou, E; Zlobec, I; et al. Proposal for a 10-high-power-fields scoring rnethod for the assessment of tumor budding in colorectal cancer. MODERN PATHOLOGY 26:295-301(2013).
- Lang, LX; Li, WH; et al. New Methods for Labeling RGD Peptides with Bromine-76. THERANOSTICS 1:341-353(2011).