BNC1
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Official Full Name
basonuclin 1 -
Overview
The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair;follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a;regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. This gene seems;to have multiple alternatively spliced transcript variants, but their full-length nature is not known yet. There seems;to be evidence of multiple polyadenylation sites for this gene. -
Synonyms
BNC1;basonuclin 1;zinc finger protein basonuclin-1;AW546376;AI047752;BNC;BNC1_HUMAN;BSN1;HsT19447
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BNC1-3049H | Recombinant Human BNC1 protein, His-tagged | E.coli | Human | His | 549 - 740 aa | |
| BNC1-291H | Recombinant Human BNC1 Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| BNC1-301336H | Recombinant Human BNC1 protein, GST-tagged | E.coli | Human | GST | Met549-Lys740 |
|
| BNC1-3754HF | Recombinant Full Length Human BNC1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 994 amino acids |
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| BNC1-561H | Recombinant Human BNC1 Protein, His-tagged | E.coli | Human | His | Cys43~Phe246 |
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Involved Pathway
BNC1 involved in several pathways and played different roles in them. We selected most pathways BNC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BNC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
BNC1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by BNC1 itself. We selected most functions BNC1 had, and list some proteins which have the same functions with BNC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
BNC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BNC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BNC1.
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References
- Feuerborn, A; Mathow, D; et al. Basonuclin-1 modulates epithelial plasticity and TGF-beta 1-induced loss of epithelial cell integrity. ONCOGENE 34:1185-1195(2015).
- Ricketts, CJ; Hill, VK; et al. Tumor-Specific Hypermethylation of Epigenetic Biomarkers, Including SFRP1, Predicts for Poorer Survival in Patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) Project. PLOS ONE 9:-(2014).
