BEST4
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Official Full Name
bestrophin 4 -
Overview
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3 ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon. -
Synonyms
BEST4;bestrophin 4;vitelliform macular dystrophy 2 like 2 , VMD2L2;bestrophin-4;BEST 4;Bestrophin4;MGC126872;Vitelliform macular dystrophy 2 like 2;Vitelliform macular dystrophy 2 like protein 2;VMD2L2;vitelliform macular dystrophy 2-like 2;vitelliform macular dystrophy 2-like protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BEST4-10210H | Recombinant Human BEST4, His-tagged | E.coli | Human | His | 95-473a.a. | |
| BEST4-4546C | Recombinant Chicken BEST4 | Mammalian Cell | Chicken | His |
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| BEST4-0748H | Recombinant Human BEST4 Protein (Ile242-Met384), N-His tagged | E.coli | Human | His | Ile242-Met384 |
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| RFL31636HF | Recombinant Full Length Human Bestrophin-4(Best4) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-473) |
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Involved Pathway
BEST4 involved in several pathways and played different roles in them. We selected most pathways BEST4 participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with BEST4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | UNC79,SLC26A3.1,SLC29A3,SLC35A1,TRPM1B,SLC4A2A,SLC34A3,SLC2A13B,TRPC4B,SLC39A10 |
| Stimuli-sensing channels | WNK1,TRPC5A,TTYH3B,TRPM4A,ANO9,ANO4,NHEDC1,TTYH2,TTYH3,ANO7 |
| Ion channel transport | FXYD3,CUTC,CLCN7,ATP10A,ANO10,TTYH3B,TRPM1B,ANO5,TRPA1B,ATP7B |
Protein Function
BEST4 has several biochemical functions, for example, contributes_to chloride channel activity,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by BEST4 itself. We selected most functions BEST4 had, and list some proteins which have the same functions with BEST4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to chloride channel activity | GABRR3A,GABRB1,GABRQ,GABRB3,GABRZ,GABRR2A,BEST3,BEST1,GABRR2,GABRB2 |
| molecular_function | L3MBTL3,BPIFB9A,TNNT2D,UFSP1,CEP78,POLA2,EPHA6,SZT2,SBSN,CLHC1 |
Interacting Protein
BEST4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BEST4 here. Most of them are supplied by our site. Hope this information will be useful for your research of BEST4.
Dlg4
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