BDP1
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Official Full Name
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -
Overview
The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. -
Synonyms
BDP1;B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB;TAF3B1, TATA box binding protein (TBP) associated factor, RNA polymerase III, GTF3B subunit 1 , TFNR;transcription factor TFIIIB component B homolog;HSA238520;KIAA1241;KIAA1689;TFC5;TFIIIB90;TFIIIB150;B double prime 1 subunit of RNA polymerase III transcription initiation factor IIIB;BDP 1;DKFZp686C01233;DKFZp686K0831;RNA polymerase III transcription initiation factor B;TATA box binding protein (TBP) associated factor RNA polymerase III GTF3B subunit 1;TFIIIB;TFNR;Transcription factor IIIB 150;Transcription factor like nuclear regulator;OTTHUMP00000224505;transcription factor-like nuclear regulator;TATA box binding protein (TBP)-associated factor, RNA polymer;TAF3B1
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Involved Pathway
BDP1 involved in several pathways and played different roles in them. We selected most pathways BDP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BDP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
BDP1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by BDP1 itself. We selected most functions BDP1 had, and list some proteins which have the same functions with BDP1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
BDP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BDP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BDP1.
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References
- Flanders, KC; Heger, CD; et al. Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor-beta/Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 62:846-863(2014).
- Khurana, S; Melacarne, A; et al. SMAD Signaling Regulates CXCL12 Expression in the Bone Marrow Niche, Affecting Homing and Mobilization of Hematopoietic Progenitors. STEM CELLS 32:3012-3022(2014).
