BDKRB1

  • Official Full Name

    bradykinin receptor B1

  • Overview

    Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

  • Synonyms

    BDKRB1;bradykinin receptor B1;B1R;BKR1;B1BKR;BKB1R;BRADYB1;B1 bradykinin receptor;BK-1 receptor;bradykinin receptor 1;bradykinin B1 receptor

Recombinant Proteins

  • Human
  • Chicken
  • Rat
  • Zebrafish
  • Tupaia minor (Pigmy tree shrew)
  • Sus scrofa (Pig)
  • Oryctolagus cuniculus (Rabbit)
  • Mus musculus
  • Macaca fascicularis
  • Dog
  • Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus)
  • Macaca mulatta
  • Chlorocebus Aethiops
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • E.coli expression system
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
BDKRB1-183H Recombinant Human BDKRB1 Protein, GST-tagged Wheat Germ Human GST
BDKRB1-184H Recombinant Human BDKRB1 Protein, GST-tagged Wheat Germ Human GST
BDKRB1-3615C Recombinant Chicken BDKRB1 Mammalian Cell Chicken His
BDKRB1-965R Recombinant Rat BDKRB1 Protein Mammalian Cell Rat His
BDKRB1-9696Z Recombinant Zebrafish BDKRB1 Mammalian Cell Zebrafish His
BDKRB1-8471HCL Recombinant Human BDKRB1 293 Cell Lysate HEK293 Human Non
BDKRB1-1563HF Recombinant Full Length Human BDKRB1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 353 amino acids
BDKRB1-1684HF Recombinant Full Length Human BDKRB1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 353 amino acids
BDKRB1-623R Recombinant Rat BDKRB1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
BDKRB1-623R-B Recombinant Rat BDKRB1 Protein Pre-coupled Magnetic Beads HEK293 Rat
RFL10162TF Recombinant Full Length Tupaia Minor B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Tupaia minor (Pigmy tree shrew) His Full L. Full Length (1-352)
RFL13011SF Recombinant Full Length Pig B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Sus scrofa (Pig) His Full L. Full Length (1-353)
RFL22366OF Recombinant Full Length Rabbit B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Oryctolagus cuniculus (Rabbit) His Full L. Full Length (1-352)
RFL30024RF Recombinant Full Length Rat B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-337)
RFL31546MF Recombinant Full Length Mouse B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-334)
RFL33721MF Recombinant Full Length Macaca Fascicularis B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Macaca fascicularis His Full L. Full Length (1-352)
RFL34242CF Recombinant Full Length Dog B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Dog His Full L. Full Length (1-350)
RFL35284HF Recombinant Full Length Human B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-353)
RFL36031CF Recombinant Full Length Cercopithecus Pygerythrus B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Chlorocebus pygerythrus (Vervet monkey) (Cercopithecus pygerythrus) His Full L. Full Length (1-352)
RFL4343MF Recombinant Full Length Macaca Mulatta B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Macaca mulatta His Full L. Full Length (1-352)
RFL9564CF Recombinant Full Length Chlorocebus Aethiops B1 Bradykinin Receptor(Bdkrb1) Protein, His-Tagged E.coli expression system Chlorocebus Aethiops His Full L. Full Length (1-352)

    Involved Pathway

    BDKRB1 involved in several pathways and played different roles in them. We selected most pathways BDKRB1 participated on our site, such as Calcium signaling pathway,Neuroactive ligand-receptor interaction,Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with BDKRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of Actin Cytoskeleton WASL,MOS,ITGA5,PXNA,ITGB1,ARHGEF7,PFN3,PIP5K1AB,ARPC5A,MAP2K1
    Calcium signaling pathway EDNRB,GRIN1,ERBB3,NOS2A,CACNA1DA,NOS3,HTR5AL,CALM3A,ATP2A1,PPP3CCA
    Pathways in cancer RALGDS,TGFA,MMP1A,GNG11,ARHGEF12,GNAI1,RAC2,PLD1,PTCH2,COL4A1
    Inflammatory mediator regulation of TRP channels IL1RAP,PLCB3,PLA2G4A,GNAS,PRKCB,CALML3,PIK3CB,ACCN4,CALM1,CYP4A12A
    Complement and coagulation cascades SERPINA1E,C4BPA,CD59A,MBL2,PLAT,PLAU,C4A,CFB,CR1L,C8B
    Neuroactive ligand-receptor interaction SSTR5,PRL2,CHRNA9,TAAR6,MC5RB,FPR3,AVPR1B,OXTR,DRD7,TAAR13C

    Protein Function

    BDKRB1 has several biochemical functions, for example, bradykinin receptor activity,peptide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BDKRB1 itself. We selected most functions BDKRB1 had, and list some proteins which have the same functions with BDKRB1. You can find most of the proteins on our site.

    Function Related Protein
    peptide binding AVPR1A,ANPEPA,HCRTR1,PPIA,GPR22,FURIN,Ctsl,FNTB,RNPEPL1,PCSK5
    bradykinin receptor activity BDKRB2
    protein binding XAGE3,GCH1,C18orf1,ILK,BAG1,RRP8,TNIP2,TTC8,ARF4,DAK

    Interacting Protein

    BDKRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BDKRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BDKRB1.

    KNG1;KNG1

    Resources

    Research Area

    Peptide Receptors on Endothelial Cells
    Peptide Hormone G Protein-Coupled Receptors
    Plasmin/Plasminogen and Kallikrein/Kinin Systems

    References

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