BANK1
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Official Full Name
B-cell scaffold protein with ankyrin repeats 1 -
Overview
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. -
Synonyms
BANK1;B-cell scaffold protein with ankyrin repeats 1;B-cell scaffold protein with ankyrin repeats;BANK;FLJ20706;FLJ34204
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BANK1-069H | Recombinant Human BANK1 protein, GST-tagged | Wheat Germ | Human | GST |
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| BANK1-2288M | Recombinant Mouse BANK1 Protein | Mammalian Cell | Mouse | His |
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| BANK1-1696H | Recombinant Human BANK1 Protein (1-785 aa), His-tagged | Yeast | Human | His | 1-785 aa |
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| BANK1-1811HF | Recombinant Full Length Human BANK1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 755 amino acids |
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| BANK1-960M | Recombinant Mouse BANK1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| BANK1-960M-B | Recombinant Mouse BANK1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
BANK1 involved in several pathways and played different roles in them. We selected most pathways BANK1 participated on our site, such as B Cell Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BANK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | DOK1B,CARD11,PIK3R2,IFITM1,GRB2,PIK3CB,PRKCB,CD79A,Cd79a,CD79B |
Protein Function
BANK1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BANK1 itself. We selected most functions BANK1 had, and list some proteins which have the same functions with BANK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SAC3D1,IFT172,BRAT1,BCL2L12,SMO,C19orf73,RP9,COL4A3,FAM161A,ELMO3 |
Interacting Protein
BANK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BANK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BANK1.
Traf1;Stat3
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References
- Silva, JD; Addobbati, C; et al. Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations. CURRENT GENOMICS 15:52-65(2014).
- Sun, F; Xu, J; et al. Polymorphisms in the FAM167A-BLK, but not BANK1, are associated with primary Sjogren's syndrome in a Han Chinese population. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 31:704-710(2013).
