B3GALTL
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Official Full Name
beta 1,3-galactosyltransferase-like -
Overview
The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS). -
Synonyms
B3GALTL;beta 1,3-galactosyltransferase-like;beta-1,3-glucosyltransferase;B3Glc T;B3GTL;B3GlcT;Beta 1,3 galactosyltransferase like;Beta 3 galactosyltransferase like;Beta3GlcT;Galactosyltransferase;GalT;beta 3-glycosyltransferase-like;beta-3-glycosyltransferase-like;UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like;Gal-T;B3Glc-T;beta3Glc-T
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- Human Cell
- In Vitro Cell Free System
- HEK293
- GST
- His
- His&Fc
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| B3GALTL-10098H | Recombinant Human B3GALTL, GST-tagged | E.coli | Human | GST | 199-498a.a. | |
| B3GALTL-013H | Recombinant Human B3GALTL protein, GST-tagged | Wheat Germ | Human | GST |
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| B3GALTL-2235M | Recombinant Mouse B3GALTL Protein | Mammalian Cell | Mouse | His |
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| B3GALTL-459H | Recombinant Human B3GALTL, His tagged | Human Cell | Human | His&Fc | 29-494 a.a. |
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| B3GALTL-1103HCL | Recombinant Human B3GALTL cell lysate | Human Cell | Human | Non |
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| B3GALTL-1716HF | Recombinant Full Length Human B3GALTL Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 498 amino acids |
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| B3GALTL-926M | Recombinant Mouse B3GALTL Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| B3GALTL-926M-B | Recombinant Mouse B3GALTL Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
B3GALTL involved in several pathways and played different roles in them. We selected most pathways B3GALTL participated on our site, such as Metabolism of proteins,O-glycosylation of TSR domain-containing proteins,O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GALTL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Other types of O-glycan biosynthesis | GLT25D2,POFUT2,B3GAT2,LFNG,PLOD3,POMGNT1,B4GALT3,OGT.1,POMT2,COLGALT2 |
| O-glycosylation of TSR domain-containing proteins | ADAMTS8,ADAMTS20,ADAMTS4,THSD1,C8orf84,ADAMTS1,SPON1B,SPON2,THSD7A,ADAMTS10 |
| Metabolism of proteins | NSMCE4A,GPR116,ADAMTS8,ADAMTSL3,MIA3,TIMM44,CKAP4,MPDU1,MPDU1A,DPAGT1 |
| Post-translational protein modification | NAPAA,BET1,TMED10,DHPS,MGAT4B,CTAGE5,MPDU1B,CBX8,GNE,NEU4 |
| O-linked glycosylation | ADAMTS20,ADAMTS3,ADAMTS5,SSPO,B3GNT6,MUC15,ADAMTSL4,MUC13,B3GNT2A,MUCL1 |
Protein Function
B3GALTL has several biochemical functions, for example, transferase activity, transferring glycosyl groups. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GALTL itself. We selected most functions B3GALTL had, and list some proteins which have the same functions with B3GALTL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity, transferring glycosyl groups | UGT5C3,B3GNT8,UGT5A5,PNP5B,UGT5A4,GBGT1,B3GALT6,UGT1B3,ST6GALNAC1.2,MGAT4C |
Interacting Protein
B3GALTL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GALTL here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GALTL.
FGFR1OP;AK1;EMC2;SMC6
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References
- Reis, LM; Semina, EV; et al. Genetics of anterior segment dysgenesis disorders. CURRENT OPINION IN OPHTHALMOLOGY 22:314-324(2011).
- Aliferis, K; Marsal, C; et al. A novel nonsense B3GALTL mutation confirms Peters plus syndrome in a patient with multiple malformations and Peters anomaly. OPHTHALMIC GENETICS 31:205-208(2010).
