ATF7IP
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Official Full Name
activating transcription factor 7 interacting protein -
Overview
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional;coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 (PubMed;19106100)). -
Synonyms
ATF7IP;activating transcription factor 7 interacting protein;activating transcription factor 7-interacting protein 1;FLJ10688;p621;hAM;ATF-IP;ATF-interacting protein;ATF7-interacting protein;ATFa-associated modulator;MBD1-containing chromatin as
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATF7IP-2041C | Recombinant Chicken ATF7IP | Mammalian Cell | Chicken | His |
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| ATF7IP-2071M | Recombinant Mouse ATF7IP Protein | Mammalian Cell | Mouse | His |
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| ATF7IP-4798Z | Recombinant Zebrafish ATF7IP | Mammalian Cell | Zebrafish | His |
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| ATF7IP-8628HCL | Recombinant Human ATF7IP 293 Cell Lysate | HEK293 | Human | Non |
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| ATF7IP-817M | Recombinant Mouse ATF7IP Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ATF7IP-817M-B | Recombinant Mouse ATF7IP Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ATF7IP involved in several pathways and played different roles in them. We selected most pathways ATF7IP participated on our site, such as Chromatin modifying enzymes,Chromatin organization,PKMTs methylate histone lysines, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATF7IP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin organization | PADI6,DNMT3A,ATXN7,KDM5A,TAF6L,ANO9A,ING4,JADE1,SETD3,KAT8 |
| Chromatin modifying enzymes | ENY2,SMARCD3B,PRMT5,SMARCC1B,SUZ12A,PADI6,KDM2A,KDM4D,BRPF1,MORF4L2 |
| PKMTs methylate histone lysines | SMYD2A,EHMT2,SMYD3,SUZ12A,SUZ12B,AEBP2,RBBP5,PRDM16,ASH2L,SETD3 |
Protein Function
ATF7IP has several biochemical functions, for example, ATPase activity,protein binding,transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATF7IP itself. We selected most functions ATF7IP had, and list some proteins which have the same functions with ATF7IP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription corepressor activity | ASXL1,FOXP3,SKOR1A,HDAC7,KCNIP3,UBP1,RELB,SKIL,RUNX1T1,DR1 |
| protein binding | EIF2B4,LILRB4,STEAP3,XPO5,ZBTB17,APOOL,PAFAH1B3,CDC45,HSCB,FBXO28 |
| ATPase activity | ABCA5,MYH9,CLPB,ATAD1A,ENTPD2,KIFC2,EIF4A1B,MLH3,KIF9,HSPA8 |
Interacting Protein
ATF7IP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATF7IP here. Most of them are supplied by our site. Hope this information will be useful for your research of ATF7IP.
SMAD4;SP1;LAMA5;FLNB;STBD1;TFAP2A;COL4A2;LAMC1;NPR1;HLA-B;FLT4;MCAM;TTC3;CDH11;ACTB;RPS3A;ACTG1;PKD1;SPTBN1
Resources
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References
- Teramachi, J; Hiruma, Y; et al. Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease. JOURNAL OF BONE AND MINERAL RESEARCH 28:1489-1500(2013).
- Cayado-Gutierrez, N; Moncalero, VL; et al. Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN. CELL STRESS & CHAPERONES 18:243-249(2013).
