ATF5
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Official Full Name
activating transcription factor 5 -
Synonyms
ATF5;activating transcription factor 5;cyclic AMP-dependent transcription factor ATF-5;transcription factor ATFx;cAMP-dependent transcription factor ATF-5;ATFX;HMFN0395;FLJ34666
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- His&GST
- GST
- Non
- N-His&C-Myc
- His&Fc&Avi
Involved Pathway
ATF5 involved in several pathways and played different roles in them. We selected most pathways ATF5 participated on our site, such as Myometrial Relaxation and Contraction Pathways,Signaling events mediated by PRL, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATF5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Myometrial Relaxation and Contraction Pathways | RAMP1,MAFF,RGS6,GABPB1,RGS5,MYLK2,RAMP3,ACTA1,GPR182,IGFBP4 |
| Signaling events mediated by PRL | LRP8,PTP4A3,RABGGTB,RABGGTA,PTP4A2,PTP4A1 |
Protein Function
ATF5 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATF5 itself. We selected most functions ATF5 had, and list some proteins which have the same functions with ATF5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | GATAD1,E2F1,LHX2B,ASCL1A,NR1D2B,ENG1A,PPARD,HOXA4A,NANOGP8,MXTX2 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | SOX9A,ZSCAN18,SOX30,ZNF434,FOXC1B,ETV4,FOXL1,ZNF174,JUNB,OVOL3 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | MAFGB,ATF3,MYF6,IRF2,HIF1A,GATA2B,FEZF2,NEUROD2,GATA3,ALX4 |
| transcription factor activity, sequence-specific DNA binding | HOXA3A,CDX2,ZFP36L1,POUV,HOXC4A,ZNF789,RUNX2A,ZNF35,ENO1,ELF3 |
| kinase binding | NTRK1,CDC6,SGOL1,DGKQ,C2orf44,DUSP12,HPCA,JAKMIP1,PTPN22,EMP2 |
| protein binding | SNRPD1,MYF5,TTK,CAP2,MAPK11,RPP25,IKBKE,STAT6,RHNO1,TMEM140 |
| chromatin binding | POU5F3,GM606,PHC1,SIN3B,NR5A1,SNAI2,ARID3A,HMGB2B,IFT74,TWIST2 |
| transcription corepressor activity | TRIM22,CDX2,HDAC7,MYBBP1A,KDM5B,BASP1,ZNF274,HSF4,APEX1,ARHGAP35 |
| RNA polymerase II regulatory region sequence-specific DNA binding | OSR2,TFAP2C,ZBTB16A,CREB3L4,IKZF5,PRDM15,E4F1,PHOX2B,ZNF549,RXRA |
Interacting Protein
ATF5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATF5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATF5.
DISC1;CEBPA;CEBPG;BATF;CCND3;CDC34;ATXN1;EP300;GIT2;TRIB3
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References
- Al-Bahrani, R; Tuertcher, D; et al. Differential SIRT1 Expression in Hepatocellular Carcinomas and Cholangiocarcinoma of the Liver. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:3-9(2015).
- Munakata, S; Tashiro, Y; et al. Inhibition of Plasmin Protects Against Colitis in Mice by Suppressing Matrix Metalloproteinase 9-Mediated Cytokine Release From Myeloid Cells. GASTROENTEROLOGY 148:565-+(2015).
