ARMCX3
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Official Full Name
armadillo repeat containing, X-linked 3 -
Overview
This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. -
Synonyms
ARMCX3;armadillo repeat containing, X-linked 3;armadillo repeat-containing X-linked protein 3;ALEX3;1200004E24Rik;ARM protein lost in epithelial cancers on chromosome X 3;Arm protein lost in epithelial cancers, X chromosome, 3;Armadillo repeat containing X linked protein 3;dJ545K15.2;DKFZp781N1954;KIAA0443;MGC12199
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
ARMCX3 involved in several pathways and played different roles in them. We selected most pathways ARMCX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARMCX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ARMCX3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARMCX3 itself. We selected most functions ARMCX3 had, and list some proteins which have the same functions with ARMCX3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ARMCX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARMCX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARMCX3.
MAF1;CSNK2A1;CLTC;IMMT
Resources
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References
- Serrat, R; Lopez-Domenech, G; et al. The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3. PLOS ONE 8:-(2013).
- Lopez-Domenech, G; Serrat, R; et al. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. NATURE COMMUNICATIONS 3:-(2012).
- Mou, ZM; Tapper, AR; et al. The Armadillo Repeat-containing Protein, ARMCX3, Physically and Functionally Interacts with the Developmental Regulatory Factor Sox10. JOURNAL OF BIOLOGICAL CHEMISTRY 284:13629-13640(2009).
