ARID2
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Official Full Name
AT rich interactive domain 2 (ARID, RFX-like) -
Overview
ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates;ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 (PubMed 15985610)). -
Synonyms
ARID2;AT rich interactive domain 2 (ARID, RFX-like);AT-rich interactive domain-containing protein 2;BAF200;DKFZp686G052;FLJ30619;KIAA1557;ARID domain containing protein 2;ARID domain-containing protein 2;ARID2_HUMAN;AT rich interactive domain 2 (ARID, RFX like);AT rich interactive domain containing protein 2;BAF;BRG1 associated factor 200;BRG1-associated factor 200;DKFZp779P0222;p200;Zinc finger protein with activation potential;zip zap;zipzap;Zipzap/p200
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARID2-4844Z | Recombinant Zebrafish ARID2 | Mammalian Cells | Zebrafish | His |
|
Involved Pathway
ARID2 involved in several pathways and played different roles in them. We selected most pathways ARID2 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,RMTs methylate histone arginines, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARID2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin modifying enzymes | ATXN7L3,SMARCB1A,YEATS4,RUVBL2,KDM6AL,RBBP4,PHF15,USP22,SMARCD3,ING5A |
| Chromatin organization | PADI6,KDM4A,MBD3A,PHF20B,MORF4L1,ACTL6B,CHD4,SAP30,CCDC101,PRMT6 |
| RMTs methylate histone arginines | WDR77,SMARCD3B,SMARCA2,SMARCD3,SMARCB1A,SMARCD1,PRMT7,PBRM1L,COPRS,SMARCA4 |
Protein Function
ARID2 has several biochemical functions, for example, DNA binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARID2 itself. We selected most functions ARID2 had, and list some proteins which have the same functions with ARID2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CLCA5,ZNF193,TRIM26,ZFP641,NRXN3B,PDE3A,FAM20B,ZNF777,PRKCDA,ROCK2 |
| DNA binding | ISL1L,TIGD4,TAF4B,FOXF2,DDX3X,PCBP3,FOSB,PHOX2BB,DDB2,NFYAL |
Interacting Protein
ARID2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARID2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARID2.
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References
- Kruger, AV; Jelier, R; et al. Comprehensive single cell-resolution analysis of the role of chromatin regulators in early C. elegans embryogenesis. DEVELOPMENTAL BIOLOGY 398:153-162(2015).
- Yoshikawa, Y; Sato, A; et al. Biallelic germline and somatic mutations in malignant mesothelioma: Multiple mutations in transcription regulators including mSWI/SNF genes. INTERNATIONAL JOURNAL OF CANCER 136:560-571(2015).
