AQP5
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Official Full Name
aquaporin 5 -
Overview
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to;the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary;secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. -
Synonyms
AQP5;aquaporin 5;aquaporin-5;AQP 5;AQP-5;AQP5_HUMAN;OTTHUMP00000241927
Recombinant Proteins
- Human
- Mouse
- Rat
- Pig
- Mus musculus
- Milnesium tardigradum (Water bear) (Tardigrade)
- Sus scrofa (Pig)
- Sheep
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- HEK293
- His
- Non
- His&GST
- His&Fc&Avi
- His&KSI
Involved Pathway
AQP5 involved in several pathways and played different roles in them. We selected most pathways AQP5 participated on our site, such as Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with AQP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Salivary secretion | DMBT1,Adcy4,BEST2,ATP1B1,CALM4,GNAQ,CAMP,LYZ1,Slc4a2,ATP1A3 |
Protein Function
AQP5 has several biochemical functions, for example, glycerol channel activity,protein binding,water channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AQP5 itself. We selected most functions AQP5 had, and list some proteins which have the same functions with AQP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TP63,OTOF,COLGALT2,ADAP1,TFF1,PIDD1,DHPS,DHRS1,SERPINB5,HIST2H4A |
| water channel activity | AQP3A,AQP1,AQP8B,AQP9,AQP6,AQP1A.1,AQP2,AQP7,AQP10,AQP10B |
| glycerol channel activity | MIP,AQP1,AQP8B,AQP8A.1,AQP3,AQP1A.1,AQP8A.2,MIPB,MIPA,AQP10 |
Interacting Protein
AQP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AQP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of AQP5.
MDFI;KRT31;KRT40;HNRPK;NOTCH2NL;CREB3;WNT2;GLRX
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References
- Tsai, MC; Lin, HJ; et al. High-altitude pulmonary edema can be prevented by heat shock protein 70-mediated hyperbaric oxygen preconditioning. JOURNAL OF TRAUMA AND ACUTE CARE SURGERY 77:585-591(2014).
- Tran, TL; Bek, T; et al. Altered aquaporin expression in glaucoma eyes. APMIS 122:772-780(2014).
