APPBP2
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Official Full Name
amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -
Overview
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimers disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. -
Synonyms
APPBP2;amyloid beta precursor protein (cytoplasmic tail) binding protein 2;amyloid protein-binding protein 2;Hs.84084;KIAA0228;PAT1;protein interacting with APP tail 1;Amyloid protein binding protein 2;APP BP2;APP-BP2;amyloid beta precursor protein-binding protein 2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rat
- Rhesus macaque
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- His
- GST
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
APPBP2 involved in several pathways and played different roles in them. We selected most pathways APPBP2 participated on our site, such as Regulation of Androgen receptor activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with APPBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Androgen receptor activity | NR0B1,SENP1,GATA2,SMARCE1,SMARCA2,KAT7,TRIM24,HOXB13,SRY,SPDEF |
Protein Function
APPBP2 has several biochemical functions, for example, microtubule motor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APPBP2 itself. We selected most functions APPBP2 had, and list some proteins which have the same functions with APPBP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ADAM33,IRF6,C10orf137,IRF7,DPYSL3,NR2F1,IKZF1,H2AFZ,GP6,MEX3C |
| microtubule motor activity | KLC1A,KIF1B,DYNC1I2,KIF6,DNAH9,DYNC1LI1,KIF21A,SMC3,DNAH14,KIF5B |
Interacting Protein
APPBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APPBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of APPBP2.
FSTL1;TBL3;RRS1;WDR24;NFYA
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