APOBEC3C
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Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C -
Overview
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. -
Synonyms
APOBEC3C;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C;probable DNA dC->dU-editing enzyme APOBEC-3C;APOBEC1L;ARDC2;ARDC4;ARP5;bK150C2.3;PBI;Phorbolin I protein;APOBEC1 like;Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C;MGC19485;Probable DNA dC dU editing enzyme APOBEC 3C;phorbolin I;A3C
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- Mammalian cells
- HEK293T
- GST
- Non
- His
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
APOBEC3C involved in several pathways and played different roles in them. We selected most pathways APOBEC3C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOBEC3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APOBEC3C has several biochemical functions, for example, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOBEC3C itself. We selected most functions APOBEC3C had, and list some proteins which have the same functions with APOBEC3C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | EIF3A,NONO,IFIT5,NME1,SMNDC1,ZFC3H1,RBM4B,KIAA0020,ZCRB1,NCOA5 |
| protein binding | ZHX3,SPON1,ITM2A,GTF2H1,FCER1G,ACTR10,HTR1B,RNF126,SMR3B,LOXL2 |
| zinc ion binding | EDEM3,RNF19B,HERC2,MORC3,MMP14A,DTX1,RAG2,RNF180,ADAM18,BTR12 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | APOBEC2A,APOBEC3D,APOBEC4,APOBEC2B |
Interacting Protein
APOBEC3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOBEC3C here. Most of them are supplied by our site. Hope this information will be useful for your research of APOBEC3C.
RBMY1A1;RBMX;RBMY1F;SRPK2;CNBP;TRAF3;hscA;ssdna_dcdgm;FN1;RPL10;Eif3i
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References
- Pauklin, S; Burkert, JS; et al. Alternative Induction of Meiotic Recombination From Single-Base Lesions of DNA Deaminases. GENETICS 182:41-54(2009).
