APBA3
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Official Full Name
amyloid beta (A4) precursor protein-binding, family A, member 3 -
Overview
binds the cytoplasmic tail of amyloid beta precursor protein APP; also binds presenilin 1 cytoplasmic tail -
Synonyms
APBA3;amyloid beta (A4) precursor protein-binding, family A, member 3;amyloid beta A4 precursor protein-binding family A member 3;mint3;X11 like 2;X11L2;mint-3;X11-like 2 protein;adapter protein X11gamma;neuron-specific X11L2 protein;neuronal mu
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cell
- E.Coli or Yeast
- E.coli
- HEK293
- His
- His&T7
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APBA3-1756M | Recombinant Mouse APBA3 Protein | Mammalian Cell | Mouse | His |
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| Apba3-3436M | Recombinant Mouse Apba3, His-tagged | E.Coli or Yeast | Mouse | His | 571 |
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| APBA3-709R | Recombinant Rat APBA3 Protein | Mammalian Cell | Rat | His |
|
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| APBA3-7825H | Recombinant Human APBA3, His-tagged | E.coli | Human | His |
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| Apba3-8067M | Recombinant Mouse Apba3 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Val261~Leu506 |
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| APBA3-198H | Recombinant Human APBA3 Protein, His-tagged | E.coli | Human | His | Asp23-Leu278 |
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| APBA3-2316H | Recombinant Human APBA3 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| APBA3-365R | Recombinant Rat APBA3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| APBA3-365R-B | Recombinant Rat APBA3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| APBA3-614M | Recombinant Mouse APBA3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| APBA3-614M-B | Recombinant Mouse APBA3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
APBA3 involved in several pathways and played different roles in them. We selected most pathways APBA3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APBA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APBA3 has several biochemical functions, for example, beta-amyloid binding,enzyme binding,enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APBA3 itself. We selected most functions APBA3 had, and list some proteins which have the same functions with APBA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme inhibitor activity | ANGPTL3,KIAA1967,OAZ1A,PPP1R12A,UGT1A1,NOTCH1,OAZ2B,PRPSAP1,APOV1,CALU |
| beta-amyloid binding | APOEA,APBA2,CST3,CHRNA7,LDLRAD3,TSSK1B,APBB1,PION,MAPK8IP2,CLSTN1 |
| enzyme binding | BCHE,HSPA1B,APP,BTG1,MSH2,AKT1,GSTM4,HIST1H2AK,NPC2,FAM84B |
| protein binding | NPY2R,ZNF165,AP3S1,SYNJ2BP,RAB26,PPP1R37,APBB3,MED8,LYSMD1,PLK2 |
Interacting Protein
APBA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APBA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of APBA3.
BCR;TBKBP1;TANK;Azi2;EGFR;CBR1
Resources
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References
- Csiszar, A; Tucsek, Z; et al. Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in beta-amyloid generation and Alzheimer's disease. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 305:H1120-H1130(2013).
- Boesten, RJ; Schuren, FHJ; et al. Bifidobacterium breve - HT-29 cell line interaction: modulation of TNF-alpha induced gene expression. BENEFICIAL MICROBES 2:115-128(2011).
- Liu, RT; Zou, LB; et al. Liquiritigenin inhibits A beta(25-35)-induced neurotoxicity and secretion of A beta(1-40) in rat hippocampal neurons. ACTA PHARMACOLOGICA SINICA 30:899-906(2009).
