ANXA6

  • Official Full Name

    annexin A6

  • Overview

    Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.

  • Synonyms

    ANXA6;annexin A6;ANX6;CBP68;67 kDa calelectrin;Annexin VI;Annexin-6;Calphobindin-II;CPB-II;Chromobindin-20;Lipocortin VI;Protein III;p68;p70;calelectrin;calphobindin II;annexin VI (p68);OTTHUMP00000226119;OTTHUMP00000226120;OTTHUMP00000226122;calcium-binding protein p68e

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • DDK&Myc
  • Flag&His&Twin Strep
  • GST&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
ANXA6-9699H Recombinant Human ANXA, His-tagged E.coli Human His C-term-350a.a.
ANXA6-1839H Recombinant Human Annexin A6, His-tagged E.coli Human His
ANXA6-27320TH Recombinant Human ANXA6, His-tagged E.coli Human His Full L. 1-673 a.a.
ANXA6-27321TH Recombinant Human ANXA6, His-tagged E.coli Human His Full L. 1-673 a.a.
ANXA6-274Z Recombinant Zebrafish ANXA6 Mammalian Cells Zebrafish His
ANXA6-6295C Recombinant Chicken ANXA6 Mammalian Cells Chicken His
ANXA6-636H Recombinant Human ANXA6 protein, GST-tagged Wheat Germ Human GST
ANXA6-6862H Active Recombinant Human ANXA6 protein, His-tagged E.coli Human His Met1-Asp673
ANXA6-8829HCL Recombinant Human ANXA6 293 Cell Lysate HEK293 Human Non
ANXA6-001H Recombinant Human ANXA6 Protein, His-tagged E.coli Human His 1-673 a.a.
ANXA6-02H Recombinant Human ANXA6 Protein, Fc/His-tagged HEK293 Human DDK&Myc
ANXA6-0426H Recombinant Human ANXA6 Protein (Ala2-Asp673), C-His-tagged E.coli Human His Ala2-Asp673
ANXA6-0427H Recombinant Human ANXA6 Protein (Ala2-Ser251), His-tagged E.coli Human His Ala2-Ser251
ANXA6-102H Recombinant Full Length Human annexin A6 Protein, His&Flag&StrepII tagged E.coli Human Flag&His&Twin Strep Full L. 1-673aa
ANXA6-1045HF Recombinant Full Length Human ANXA6 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 673 amino acids
ANXA6-2141H Recombinant Human ANXA6 Protein, GST/His-tagged E.coli Human GST&His
ANXA6-3113H Recombinant Human ANXA6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
ANXA6-572H Recombinant Human ANXA6 Protein, His-tagged E.coli Human His Ala2~Ser251
Anxa6-573M Recombinant Mouse Anxa6 Protein, His-tagged E.coli Mouse His Ser251~Leu504

    Involved Pathway

    ANXA6 involved in several pathways and played different roles in them. We selected most pathways ANXA6 participated on our site, such as Calcium Regulation in the Cardiac Cell,Muscle contraction,Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium Regulation in the Cardiac Cell GJB1,RGS14,CHRM5,GNB3B,RGS20,KCNJ5,RGS5A,AKR1C1,CX27.5,RGS11
    Muscle contraction DESMB,TNNT3,TNNI2A.4,TMOD3,CMLC1,MYL12A,SORBS3,MYL12B,TNNT3B,TNNI2B.1
    Prostaglandin Synthesis and Regulation ANXA5,CC10,ANXA4,S100A6,ANXA3,S100A10,ANXA2

    Protein Function

    ANXA6 has several biochemical functions, for example, GTP binding,calcium ion binding,calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA6 itself. We selected most functions ANXA6 had, and list some proteins which have the same functions with ANXA6. You can find most of the proteins on our site.

    Function Related Protein
    protein homodimerization activity KIF20B,DMRT2B,PVRL1B,MBL1,LILRB1,KYNU,CHMP1A,XCL1,OLIG2,TCF12
    calcium-dependent protein binding NRXN1,SNAP25,S100B,SYN1,CCDC167,CLEC4M,CASQ2,STX2,ALG2,CHP1
    GTP binding RHOGD,GUCY2E,RAB40C,RAB9B,RHOG,RHOC,SEPT5,NMUR2,SEPT2,RAB28
    calcium ion binding LETM1,SLC24A4A,PCDH18B,CDH4,PLCD4,LDLRB,PLCD3A,PCDH2AB2,PCDHGA2,SLC24A4
    ligand-gated ion channel activity ZACN,Chrng,CHRNB2,TRPA1B,GABRB1,CHRNA5,CHRNA4,P2RX2,CHRNA3,CLCA5
    protein binding AHCYL2,GNB5,NOS3,HIST1H4B,ELK4,NSG1,GEMIN6,RAB18,MYD88,XRCC5
    lipid binding PTGS2,CYP21A1,MARK2,ALOX8,AP2M1A,FABP7A,CYTH1,FABP9,OSBPL6,ATP5G1
    cholesterol binding TSPO,OSBPL5,ABCA1,NPC1,OSBP2,STARD3,NPC2,APOC3,APOA4B.2,OSBPL8
    calcium-dependent phospholipid binding DOC2D,ANXA3A,ANXA5,TC2N,ANXA3,CCDC167,SYT5B,SYT11A,SYTL1,SYT10

    Interacting Protein

    ANXA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA6.

    ACTB;ERBB2;MLH1;pilB;ruvB;sucA;CDC73;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;MME;CD9;GRB2;TJP1;SF1

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