ANKRD12
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Official Full Name
ankyrin repeat domain 12 -
Overview
This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
ANKRD12;ankyrin repeat domain 12;ankyrin repeat domain-containing protein 12;FLJ20053;GAC 1;KIAA0874;ankyrin repeat-containing cofactor 2;ANCO1;GAC-1;ANCO-2;Nbla00144
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ANKRD12-10497Z | Recombinant Zebrafish ANKRD12 | Mammalian Cell | Zebrafish | His |
|
Involved Pathway
ANKRD12 involved in several pathways and played different roles in them. We selected most pathways ANKRD12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKRD12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ANKRD12 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ANKRD12 itself. We selected most functions ANKRD12 had, and list some proteins which have the same functions with ANKRD12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | ABI2A,MTMR11,TMEM143,CCDC41,ZNF79,FADS3,TNKS1BP1,CCDC106B,SLC6A8,LRRC8E |
Interacting Protein
ANKRD12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKRD12 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKRD12.
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References
- Tsytlonok, M; Sormanni, P; et al. Subdomain Architecture and Stability of a Giant Repeat Protein. JOURNAL OF PHYSICAL CHEMISTRY B 117:13029-13037(2013).
- Tiede, C; Tang, AAS; et al. Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. PROTEIN ENGINEERING DESIGN & SELECTION 27:145-155(2014).
