ANKRD11
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Official Full Name
ankyrin repeat domain 11 -
Overview
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent;activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by;macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay,;seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related;pseudogenes exist on chromosomes 2 and X. -
Synonyms
ANKRD11;ankyrin repeat domain 11;ankyrin repeat domain-containing protein 11;LZ16;T13;ANCO 1;ANCO1;Ankyrin repeat containing cofactor 1;Ankyrin repeat domain containing protein 11;ankyrin repeat-containing cofactor 1;ankyrin repeat-containing protein 11;nasopharyngeal carcinoma susceptibility protein;KBGS;ANCO-1
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Involved Pathway
ANKRD11 involved in several pathways and played different roles in them. We selected most pathways ANKRD11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKRD11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
ANKRD11 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ANKRD11 itself. We selected most functions ANKRD11 had, and list some proteins which have the same functions with ANKRD11. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
ANKRD11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKRD11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKRD11.
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References
- Liao, HI; Olson, CA; et al. mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 284:17512-17520(2009).
- Ohkura, T; Taniguchi, S; et al. Detection of the novel autoantibody (anti-UACA antibody) in patients with Graves' disease. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 321:432-440(2004).
