ANKK1
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Official Full Name
ankyrin repeat and kinase domain containing 1 -
Overview
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. -
Synonyms
ANKK1;ankyrin repeat and kinase domain containing 1;ankyrin repeat and protein kinase domain-containing protein 1;X kinase;sgK288;X-kinase;sugen kinase 288;protein kinase PKK2;PKK2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ANKK1-566H | Recombinant Human ANKK1 protein, GST-tagged | Wheat Germ | Human | GST |
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| ANKK1-7122Z | Recombinant Zebrafish ANKK1 | Mammalian Cell | Zebrafish | His |
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| ANKK1-1437HF | Recombinant Full Length Human ANKK1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 765 amino acids |
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Involved Pathway
ANKK1 involved in several pathways and played different roles in them. We selected most pathways ANKK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ANKK1 has several biochemical functions, for example, ATP binding,kinase activity,protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANKK1 itself. We selected most functions ANKK1 had, and list some proteins which have the same functions with ANKK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| kinase activity | SPS2,CDKN1D,KITA,PFKMB,NLK1,MAP4K6,EGFRA,PKZ,MAPK8B,MAPK12A |
| ATP binding | MAP2K2,COASY,NEK3,LTK,KIF12,ATP1A1A.4,PAPD4,UBE2M,CERK,FIGN |
| transferase activity | MAPKAPK2B,SULT1ST6,GGCTB,FUT9D,PRKCHA,PTK2AA,FBLL1,ELOVL4A,BMPR2A,ZDHHC15B |
| protein kinase activity | PKDCCA,MAPK14B,NPR2,NPR1,LRRK2,MINK1,PTK2AA,DCLK2,PKN3,SGK3 |
Interacting Protein
ANKK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKK1.
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