AMPH
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Official Full Name
amphiphysin -
Overview
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11. -
Synonyms
AMPH;amphiphysin;amphiphysin (Stiff Man syndrome with breast cancer 128kDa autoantigen) , amphiphysin (Stiff Mann syndrome with breast cancer 128kD autoantigen);amphiphysin I;amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen);AMP
Recombinant Proteins
- Zebrafish
- Chicken
- Mouse
- Human
- Rat
- Mammalian Cell
- Wheat Germ
- E.Coli or Yeast
- HEK293
- E.coli
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
AMPH involved in several pathways and played different roles in them. We selected most pathways AMPH participated on our site, such as Endocytosis,Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fc gamma R-mediated phagocytosis | PIK3R5,MARCKS,MAPK1,WAS,PLA2G4F,VASP,PLD2,PPAP2C,PLA2G6,LIMK1 |
| Endocytosis | CHMP5B,GRK4,HSPA1L,ARFGEF2,PARD6GB,HLA-F,WASB,EPS15,VPS25,AGAP2 |
Protein Function
AMPH has several biochemical functions, for example, phospholipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMPH itself. We selected most functions AMPH had, and list some proteins which have the same functions with AMPH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SMARCC1,SLMAP,AES,C14orf166,CDH5,GALR1,HNRNPUL1,RAB5B,LCAT,IFT20 |
| phospholipid binding | APOA1,APOM,SYT14,SPTBN2,STAP1,ABCA1,PSD4,PREX1,LC3,PICALMB |
Interacting Protein
AMPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMPH here. Most of them are supplied by our site. Hope this information will be useful for your research of AMPH.
DNM1;DNM2;Ap2a2;Necap1;SYNJ1
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