ALKBH5
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Official Full Name
alkB, alkylation repair homolog 5 (E. coli) -
Synonyms
ALKBH5;alkB, alkylation repair homolog 5 (E. coli);OFOXD1, oxoglutarate and iron dependent oxygenase domain containing;probable alpha-ketoglutarate-dependent dioxygenase ABH5;FLJ20308;AlkB, alkylation repair homolog 5;OFOXD;OFOXD1;Oxoglutarate and iron-dependent oxygenase domain containing;alkylated DNA repair protein alkB homolog 5;ABH5
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Human
- Rat
- Mammalian Cell
- Wheat Germ
- HEK293
- Insect cells
- In Vitro Cell Free System
- Insect Cells
- E.coli
- His
- GST
- Non
- Flag
- His&Fc&Avi
Involved Pathway
ALKBH5 involved in several pathways and played different roles in them. We selected most pathways ALKBH5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALKBH5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ALKBH5 has several biochemical functions, for example, metal ion binding,oxidative RNA demethylase activity,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors. Some of the functions are cooperated with other proteins, some of the functions could acted by ALKBH5 itself. We selected most functions ALKBH5 had, and list some proteins which have the same functions with ALKBH5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidative RNA demethylase activity | FTO |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | P4HTM,KDM5D,EGLN1,KDM5BB,JHDM1D,KDM5B,EGLN3,TYW5,ALKBH4,C14orf169 |
| metal ion binding | ZNF444,TOPAZ1,ZNFX1,BSN,CAR15,ATP2B2,PGGT1B,CYBA,PRICKLE1B,SCAPER |
| poly(A) RNA binding | PRAC,ATXN2,RBM22,SNW1,DDX55,LRPPRC,ROCK2,DHX16,NOL6,MRPL44 |
Interacting Protein
ALKBH5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALKBH5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALKBH5.
ssdna_dtdc;THOC7
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